recent publications

• academic article

  • Yin, X., Cheng, H., Lin, Y., Wineinger, N. E., Zhou, F., Sheng, Y., Yang, C., Li, P., Li, F., Shen, C., Yang, S., Schork, N. J., et al. A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in han chinese PLoS One  2015 10:e0125369  DOI:10.1371/journal.pone.0125369  PMID:25933357  PMCID:PMC4416725
  • Wang, J., Han, X., Wong, C. C., Cheng, H., Aslanian, A., Xu, T., Leavis, P., Roder, H., Hedstrom, L., Yates III, J. R., Kashina, A. Arginyltransferase ATE1 catalyzes midchain arginylation of proteins at side chain carboxylates in vivo Chemistry & Biology  2014 21:331-337  DOI:10.1016/j.chembiol.2013.12.017  PMID:24529990  PMCID:PMC4010198
  • Yin, X., Wineinger, N. E., Cheng, H., Cui, Y., Zhou, F., Zuo, X., Zheng, X., Yang, S., Schork, N. J., Zhang, X. Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population BMC Genomics  2014 15:87  DOI:10.1186/1471-2164-15-87  PMID:24479639  PMCID:PMC3909441
  • Mueller, G. A., Maleki, S. J., Johnson, K., Hurlburt, B. K., Cheng, H., Ruan, S., Nesbit, J. B., Pomes, A., Edwards, L. L., Schorzman, A., Deterding, L. J., Park, H., et al. Identification of Maillard reaction products on peanut allergens that influence binding to the receptor for advanced glycation end products Allergy  2013 68:1546-1554  DOI:10.1111/all.12261  PMID:24266677  PMCID:PMC3915869
  • Cheng, H., Chong, Y. H., Hwang, I., Tavassoli, A., Zhang, Y., Wilson, I. A., Benkovic, S. J., Boger, D. L. Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway Bioorganic & Medicinal Chemistry  2005 13:3577-3585  DOI:10.1016/j.bmc.2004.12.004  PMID:15848770
  • Cheng, H., Hwang, I., Chong, Y. H., Tavassoli, A., Webb, M. E., Zhang, Y., Wilson, I. A., Benkovic, S. J., Boger, D. L. Synthesis and biological evaluation of N-{4- 5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoro acetyl)pentyl)benzoyl}-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway Bioorganic & Medicinal Chemistry  2005 13:3593-3599  DOI:10.1016/j.bme.2004.11.049  PMID:15848772
  • Boger, D. L., Miyauchi, H., Du, W., Hardouin, C., Fecik, R. A., Cheng, H., Hwang, I., Hedrick, M. P., Leung, D., Acevedo, O., Guimaraes, C. R. W., Jorgensen, W. L., et al. Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics Journal of Medicinal Chemistry  2005 48:1849-1856  DOI:10.1021/jm049614v  PMID:15771430  PMCID:PMC2492884
  • Leung, D., Du, W., Hardouin, C., Cheng, H., Hwang, I., Cravatt, B. F., Boger, D. L. Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity Bioorganic & Medicinal Chemistry Letters  2005 15:1423-1428  DOI:10.1016/j.bmcl.2004.12.085  PMID:15713400
  • Du, W., Hardouin, C., Cheng, H., Hwang, I., Boger, D. L. Heterocyclic sulfoxide and sulfone inhibitors of fatty acid amide hydrolase Bioorganic & Medicinal Chemistry Letters  2005 15:103-106  DOI:10.1016/j.bmcl.2004.10.025  PMID:15582420
  • Porta, C., Wang, G. J., Cheng, H., Chen, Z. G., Baker, T. S., Johnson, J. E. Direct imaging of interactions between an icosahedral virus and conjugate f-ab fragments by cryoelectron microscopy and x-ray crystallography Virology  1994 204:777-788  DOI:10.1006/viro.1994.1593  PMID:7941346