Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

Neurobiology of lysophosphatidic acid signaling

Academic Article
uri icon
  • Overview
  • Research
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Fukushima, N.
  • Ye, X. Q.
  • Chun, Jerold

publication date

  • December 2002

journal

  • Neuroscientist  Journal

abstract

  • Lysophosphatidic acid (LPA), a growth factor-like lysophospholipid, induces diverse cellular responses. The identification of the first LPA receptor gene, through studies of neuroproliferative regions within the embryonic cerebral cortex, has led to the classification of a family of at least eight lysophospholipid receptors with diverse roles in organismal development and function. A growing body of literature has identified roles for LPA signaling under physiological and pathological conditions, particularly within the developing nervous system. Here the authors review features of the LPA receptor family and cellular responses of nervous system-derived cells, and discuss developmental and pathological roles for LPA signaling in the nervous system.

subject areas

  • Animals
  • Humans
  • Lysophospholipids
  • Nervous System
  • Neuroglia
  • Neurons
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled
  • Receptors, Lysophosphatidic Acid
  • Signal Transduction
scroll to property group menus

Research

keywords

  • LPA
  • developments
  • glia
  • neuroblast
  • neuron
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 1073-8584

Digital Object Identifier (DOI)

  • 10.1177/1073858402238513

PubMed ID

  • 12467376
scroll to property group menus

Additional Document Info

start page

  • 540

end page

  • 550

volume

  • 8

issue

  • 6

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support