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Schwander, M.

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    • Arnold, C. N., Xia, Y., Lin, P., Ross, C., Schwander, M., Smart, N. G., Muller, U., Beutler, B. Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis Genetics  2011 187:633-641  DOI:10.1534/genetics.110.124586  PMID:21196518  PMCID:PMC3063661
    • Schwander, M., Kachar, B., Muller, U. The cell biology of hearing Journal of Cell Biology  2010 190:9-20  DOI:10.1083/jcb.201001138  PMID:20624897  PMCID:PMC2911669
    • Pangrsic, T., Lasarow, L., Reuter, K., Takago, H., Schwander, M., Riedel, D., Frank, T., Tarantino, L. M., Bailey, J. S., Strenzke, N., Brose, N., Muller, U., et al. Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells Nature Neuroscience  2010 13:869-876  DOI:10.1038/nn.2578  PMID:20562868
    • Schwander, M., Lopes, V., Sczaniecka, A., Gibbs, D., Lillo, C., Delano, D., Tarantino, L. M., Wiltshire, T., Williams, D. S., Muller, U. A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells Journal of Neuroscience  2009 29:15810-15818  DOI:10.1523/jneurosci.4876-09.2009  PMID:20016096  PMCID:PMC2834289
    • Grillet, N., Schwander, M., Hildebrand, M. S., Sczaniecka, A., Kolatkar, A., Velasco, J., Webster, J. A., Kahrizi, K., Najmabadi, H., Kimberling, W. J., Stephan, D., Bahlo, M., et al. Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans American Journal of Human Genetics  2009 85:328-337  DOI:10.1016/j.ajhg.2009.07.017  PMID:19732867  PMCID:PMC2771534
    • Grillet, N., Kazmierczak, P., Xiong, W., Schwander, M., Reynolds, A., Sakaguchi, H., Tokita, J., Kachar, B., Muller, U. The mechanotransduction machinery of hair cells Science Signaling  2009 2:pt5  DOI:10.1126/scisignal.285pt5  PMID:19706872
    • Grillet, N., Xiong, W., Reynolds, A., Kazmierczak, P., Sato, T., Lillo, C., Dumont, R. A., Hintermann, E., Sczaniecka, A., Schwander, M., Williams, D., Kachar, B., et al. Harmonin mutations cause mechanotransduction defects in cochlear hair cells Neuron  2009 62:375-387  DOI:10.1016/j.neuron.2009.04.006  PMID:19447093  PMCID:PMC2691393
    • Schwander, M., Xiong, W., Tokita, J., Lelli, A., Elledge, H. M., Kazmierczak, P., Sczaniecka, A., Kolatkar, A., Wiltshire, T., Kuhn, P., Holt, J. R., Kachar, B., et al. A mouse model for nonsyndromic deafness (dfnb12) links hearing loss to defects in tip links of mechanosensory hair cells Proceedings of the National Academy of Sciences of the United States of America  2009 106:5252-5257  DOI:10.1073/pnas.0900691106  PMID:19270079  PMCID:PMC2664065
    • Du, X., Schwander, M., Moresco, E. M. Y., Viviani, P., Haller, C., Hildebrand, M. S., Pak, K., Tarantino, L., Roberts, A., Richardson, H., Koob, G., Najmabadi, H., et al. A catechol-O-methyltransferase that is essential for auditory function in mice and humans Proceedings of the National Academy of Sciences of the United States of America  2008 105:14609-14614  DOI:10.1073/pnas.0807219105  PMID:18794526  PMCID:PMC2567147
    • Conti, F. J., Felder, A., Monkley, S., Schwander, M., Wood, M. R., Lieber, R., Critchley, D., Mueller, U. Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle Development  2008 135:2043-2053  DOI:10.1242/dev.015818  PMID:18434420  PMCID:PMC2562324
    • Wang, H. V., Chang, L. W., Brixius, K., Wickstrom, S. A., Montanez, E., Thievessen, I., Schwander, M., Muller, U., Bloch, W., Mayer, U., Fassler, R. Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage Journal of Cell Biology  2008 180:1037-1049  DOI:10.1083/jcb.200707175  PMID:18332223  PMCID:PMC2265410
    • Schwander, M., Sczaniecka, A., Grillet, N., Bailey, J. S., Avenarius, M., Najmabadi, H., Steffy, B. M., Federe, G. C., Lagler, E. A., Banan, R., Hice, R., Grabowski-Boase, L., et al. A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function Journal of Neuroscience  2007 27:2163-2175  DOI:10.1523/jneurosci.4975-06.2007  PMID:17329413
    • Herr, D. R., Grillet, N., Schwander, M., Rivera, R., Muller, U., Chun, J. Sphingosine 1-phosphate S1P signaling is required for maintenance of hair cells mainly via activation of S1P2 Journal of Neuroscience  2007 27:1474-1478  DOI:10.1523/jneurosci.4245-06.2007  PMID:17287522
    • Senften, M., Schwander, M., Kazmierczak, P., Lillo, C., Shin, J. B., Hasson, T., Geleoc, G. S. G., Gillespie, P. G., Williams, D., Holt, J. R., Muller, U. Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells Journal of Neuroscience  2006 26:2060-2071  DOI:10.1523/jneurosci.4521-05.2006  PMID:16481439  PMCID:PMC2712835
    • Schwander, M., Shirasaki, R., Pfaff, S. L., Muller, U. Beta 1 integrins in muscle, but not in motor neurons, are required for skeletal muscle innervation Journal of Neuroscience  2004 24:8181-8191  DOI:10.1523/jneurosci.1345-04.2004  PMID:15371519
    • Leu, M., Bellmunt, E., Schwander, M., Farinas, I., Brenner, H. R., Muller, U. Erbb2 regulates neuromuscular synapse formation and is essential for muscle spindle development Development  2003 130:2291-2301  DOI:10.1242/dev.00447  PMID:12702645
    • Schwander, M., Leu, M., Stumm, M., Dorchies, O. M., Ruegg, U. T., Schittny, J., Muller, U. Beta 1 integrins regulate myoblast fusion and sarcomere assembly Developmental Cell  2003 4:673-685  DOI:10.1016/s1534-5807(03)00118-7  PMID:12737803

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