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Molecular Biology of the Cell

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Overview

articles

  • The in situ structures of mono-, di-, and trinucleosomes in human heterochromatin.  29:2450-2457. 2018
  • The effects of mechanical strain on mouse eye lens capsule and cellular microstructure.  29:1963-1974. 2018
  • Natural chromatin is heterogeneous and self-associates in vitro.  29:1652-1663. 2018
  • Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1.  29:1389-1399. 2018
  • Actin dynamics and function.  29:696-697. 2018
  • The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae.  28:2637-2649. 2017
  • Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells.  28:2531-2542. 2017
  • TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.  28:2374-2385. 2017
  • Revisiting the tubulin cofactors and Arl2 in the regulation of soluble αβ-tubulin pools and their effect on microtubule dynamics.  28:359-363. 2017
  • Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo.  27:3357-3368. 2016
  • A theoretical model of cytokinesis implicates feedback between membrane curvature and cytoskeletal organization in asymmetric cytokinetic furrowing.  27:1286-1299. 2016
  • Mechanical confinement triggers glioma linear migration dependent on formin FHOD3.  27:1246-1261. 2016
  • Structural comparison of the Caenorhabditis elegans and human Ndc80 complexes bound to microtubules reveals distinct binding behavior.  27:1197-1203. 2016
  • From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.  27:424-433. 2016
  • Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses.  27:572-587. 2016
  • Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry.  27:48-63. 2016
  • Phosphorylation-dependent inhibition of Cdc42 GEF Gef1 by 14-3-3 protein Rad24 spatially regulates Cdc42 GTPase activity and oscillatory dynamics during cell morphogenesis.  26:3520-3534. 2015
  • Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning.  26:2505-2518. 2015
  • Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors.  26:1845-1856. 2015
  • Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane.  26:1699-1710. 2015
  • A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli.  25:2866-2881. 2014
  • Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function.  25:2604-2619. 2014
  • Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle.  25:852-865. 2014
  • Protocadherin-18b interacts with Nap1 to control motor axon growth and arborization in zebrafish.  25:633-642. 2014
  • Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis.  24:3522-3533. 2013
  • The oncogenic TBX3 is a downstream target and mediator of the TGF-β1 signaling pathway.  24:3569-3576. 2013
  • A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.  24:194-209. 2013
  • Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast.  23:3348-3356. 2012
  • Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.  23:3370-3379. 2012
  • Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymerase.  23:2878-2890. 2012
  • Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.  23:1902-1916. 2012
  • Compromised mutant EFEMP1 secretion associated with macular dystrophy remedied by proteostasis network alteration.  22:4765-4775. 2011
  • A variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathway.  22:4362-4372. 2011
  • Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.  22:3725-3733. 2011
  • Overlapping kinetochore targets of CK2 and Aurora B kinases in mitotic regulation.  22:2680-2689. 2011
  • Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size.  22:2588-2600. 2011
  • A new role for the dynamin gtpase in the regulation of fusion pore expansion.  22:1907-1918. 2011
  • The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase.  22:20-32. 2011
  • C-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells.  21:4287-4298. 2010
  • A richer and more diverse future for cell biology.  21:3821-3822. 2010
  • Clathrin-mediated endocytosis: A universe of new questions.  21:3818-3819. 2010
  • Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis.  21:2944-2952. 2010
  • Inside-out regulation of L1 conformation, integrin binding, proteolysis, and concomitant cell migration.  21:1671-1685. 2010
  • Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.  21:871-884. 2010
  • Retrograde neurotrophic signaling requires a protein interacting with receptor tyrosine kinases via C2H2 zinc fingers.  21:36-49. 2010
  • Membrane insertion of the pleckstrin homology domain variable loop 1 is critical for dynamin-catalyzed vesicle scission.  20:4630-4639. 2009
  • An intramolecular signaling element that modulates dynamin function in vitro and in vivo.  20:3561-3571. 2009
  • Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits.  20:3251-3260. 2009
  • Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis.  20:2582-2592. 2009
  • Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae.  20:1772-1784. 2009
  • Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control.  20:1150-1166. 2009
  • Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells.  19:5347-5359. 2008
  • Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability.  19:4099-4109. 2008
  • Regulation of microtubule assembly and organization in mitosis by the AAA plus ATPase pontin.  19:3097-3110. 2008
  • The role of GRASP55 in Golgi fragmentation and entry of cells into mitosis.  19:2579-2587. 2008
  • Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles.  19:553-562. 2008
  • Old world arenavirus infection interferes with the expression of functional alpha-dystroglycan in the host cell.  18:4493-4507. 2007
  • Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae.  18:2779-2794. 2007
  • The RING finger domain of MDM2 is essential for MDM2-mediated TGF-β resistance.  18:2367-2377. 2007
  • Negative regulation of yeast Eps15-like Arp2/3 complex activator, Pan1p, by the Hip1R-related protein, Sla2p, during endocytosis.  18:658-668. 2007
  • Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling.  17:4760-4768. 2006
  • Ppc89 links multiple proteins, including the septation initiation network, to the core of the fission yeast spindle-pole body.  17:3793-3805. 2006
  • The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.  17:3806-3818. 2006
  • The Hsp90 chaperone complex regulates GDI-dependent Rab recycling.  17:3494-3507. 2006
  • Rtn1p is involved in structuring the cortical endoplasmic reticulum.  17:3009-3020. 2006
  • Rad22(Rad52)-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease.  17:2081-2090. 2006
  • Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress.  17:1176-1183. 2006
  • Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation.  17:1065-1074. 2006
  • Cross-talk between snurportin1 subdomains.  16:4660-4671. 2005
  • TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.  16:4572-4583. 2005
  • Large-scale profiling of Rab GTPase trafficking networks: the membrome.  16:3847-3864. 2005
  • Snx9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.  16:2058-2067. 2005
  • A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo.  16:1056-1070. 2005
  • A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis.  16:964-975. 2005
  • Rab9 GTPase regulates late endosome size and requires effector interaction for its stability.  15:5420-5430. 2004
  • Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.  15:4866-4876. 2004
  • Cross-talk of integrin alpha 3 beta 1 and tissue factor in cell migration.  15:4416-4425. 2004
  • An assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo.  15:2243-2252. 2004
  • RNA interference inhibition of Mus81 reduces mitotic recombination in human cells.  15:552-562. 2004
  • Modulation of rac localization and function by dynamin.  15:256-267. 2004
  • Organellar proteomics reveals Golgi arginine dimethylation.  15:2907-2919. 2004
  • Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast.  15:71-80. 2004
  • Molecular evolution of the Rab-escort-protein/guanine-nucleotide-dissociation-inhibitor superfamily.  14:3857-3867. 2003
  • Grr1-dependent inactivation of mth1 mediates glucose-induced dissociation of rgt1 from hxt gene promoters.  14:3230-3241. 2003
  • Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.  14:1204-1220. 2003
  • Kar9p-independent microtubule capture at bud6p cortical sites primes spindle polarity before bud emergence in saccharomyces cerevisiae.  13:4141-4155. 2002
  • Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: Actin depolymerization by Ca2+-alpha-actinin and polymerization by rho.  13:2692-2705. 2002
  • Cell cycle-dependent assembly of a Gin4-septin complex.  13:2091-2105. 2002
  • In02, a positive regulator of lipid biosynthesis, is essential for the formation of inducible membranes in yeast.  13:40-51. 2002
  • GCP5 and GCP6: two new members of the human gamma-tubulin complex.  12:3340-3352. 2001
  • Dynamin gtpase domain mutants block endocytic vesicle formation at morphologically distinct stages.  12:2578-2589. 2001
  • Bud6 directs sequential microtubule interactions with the bud tip and bud neck during spindle morphogenesis in saccharomyces cerevisiae.  11:3689-3702. 2000
  • Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton.  11:3573-3587. 2000
  • Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes.  11:3425-3439. 2000
  • Regulation of macropinocytosis by p21-activated kinase-1.  11:3341-3352. 2000
  • The APC11 RING-H2 finger mediates E2-dependent ubiquitination.  11:2315-2325. 2000
  • Regulation of mitotic inhibitor Mik1 helps to enforce the DNA damage checkpoint.  11:1-11. 2000
  • Vacuole fusion regulated by protein phosphatase 2C in fission yeast.  10:2647-2654. 1999
  • Active nucleocytoplasmic shuttling required for function and regulation of stress-activated kinase Spc1/StyI in fission yeast.  10:1395-1407. 1999
  • Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1.  10:833-845. 1999
  • Mcd4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.  10:627-648. 1999
  • The protein kinase cdr2, related to Nim1/Cdr1 mitotic inducer, regulates the onset of mitosis in fission yeast.  9:3321-3334. 1998
  • Atp- and cytosol-dependent release of adaptor proteins from clathrin-coated vesicles: A dual role for hsc70.  9:2217-2229. 1998
  • Heat stress activates fission yeast Spc1/StyI MAPK by a MEKK-independent mechanism.  9:1339-1349. 1998
  • Identification of osteopontin as a novel ligand for the integrin alpha 8 beta 1 and potential roles for this integrin-ligand interaction in kidney morphogenesis.  9:1425-1435. 1998
  • Genetic separation of FK506 susceptibility and drug transport in the yeast PDR5 ATP-binding cassette multidrug resistance transporter.  9:523-543. 1998
  • M phase phosphoprotein 10 is a human u3 small nucleolar ribonucleoprotein component.  9:437-449. 1998
  • Negative regulation of Cdc18 DNA replication protein by Cdc2.  9:63-73. 1998
  • Rangtp targets p97 to ranbp2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex.  8:2379-2390. 1997
  • Ubiquitously expressed dynamin-ii has a higher intrinsic gtpase activity and a greater propensity for self-assembly than neuronal dynamin-i.  8:2553-2562. 1997
  • Integrin alpha 6a beta 1 induces cd81-dependent cell motility without engaging the extracellular matrix migration substrate.  8:2253-2265. 1997
  • The small gtpase cdc42 initiates an apoptotic signaling pathway in jurkat t lymphocytes.  8:1687-1698. 1997
  • Mss4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport.  8:1305-1316. 1997
  • Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.  8:409-419. 1997
  • Disruption of actin filaments increases the activity of sodium-conducting channels in human myeloid leukemia cells.  7:1857-1864. 1996
  • Novel members of the cdc2-related kinase family in drosophila: Cdk4/6, cdk5, pftaire, and pitslre kinase.  7:1759-1769. 1996
  • Spatial organization of the Nim1-Wee1-Cdc2 mitotic control network in Schizosaccharomyces pombe.  7:1749-1758. 1996
  • Identification of novel m phase phosphoproteins by expression cloning.  7:1455-1469. 1996
  • cDNA cloning and characterization of a novel nucleolar protein.  7:1015-1024. 1996
  • Structural-analysis of the p62 complex, an assembly of o-linked glycoproteins that localizes near the central gated channel of the nuclear-pore complex.  6:1591-1603. 1995
  • Integrin alpha 8 beta 1 promotes attachment, cell spreading, and neurite outgrowth on fibronectin.  6:433-448. 1995
  • Formation of nuclear bodies in hepatocytes of estrogen-treated roosters.  6:345-356. 1995
  • Recruitment of epidermal growth-factor and transferrin receptors into coated pits in-vitro - differing biochemical requirements.  4:715-727. 1993
  • Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm.  3:1373-1388. 1992
  • Role of gtp hydrolysis in microtubule dynamics - information from a slowly hydrolyzable analog, gmpcpp.  3:1155-1167. 1992
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Identity

International Standard Serial Number (ISSN)

  • 1059-1524

Electronic International Standard Serial Number (EISSN)

  • 1939-4586

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