recent publications
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academic article
- Hanson, M. A., Roth, C. B., Jo, E. J., Griffith, M. T., Scott, F. L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S. M., Schuerer, S. C., Sanna, M. G., Han, G. W., et al. Crystal structure of a lipid G protein-coupled receptor Science 2012 335:851-855 DOI:10.1126/science.1215904 PMID:22344443 PMCID:PMC3338336
- Jo, E. J., Bhhatarai, B., Repetto, E., Guerrero, M., Riley, S., Brown, S. J., Kohno, Y., Roberts, E., Schurer, S. C., Rosen, H. Novel selective allosteric and bitopic ligands for the S1P(3) receptor ACS Chemical Biology 2012 7:1975-1983 DOI:10.1021/cb300392z PMID:22971058 PMCID:PMC3528827
- Sanna, M. G., Wang, S. K., Gonzalez-Cabrera, P. J., Don, A., Marsolais, D., Matheu, M. P., Wei, S. H., Parker, I., Jo, E. J., Cheng, W. C., Cahalan, M. D., Wong, C. H., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P(1) antagonist in vivo Nature Chemical Biology 2006 2:434-441 DOI:10.1038/nchembio804 PMID:16829954
- Jo, E. J., Sanna, G., Gonzalez-Cabrera, P. J., Thangada, S., Tigyi, G., Osborne, D. A., Hla, T., Parrill, A. L., Rosen, H. S1p(1)-selective in vivo-active agonists from high-throughput screening: Off-the-shelf chemical probes of receptor interactions, signaling, and fate Chemistry & Biology 2005 12:703-715 DOI:10.1016/j.chembiol.2005.04.019 PMID:15975516
- Wei, S. H., Rosen, H., Matheu, M. P., Sanna, M. G., Wang, S. K., Jo, E. J., Wong, C. H., Parker, I., Cahalan, M. D. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary t cells to lymphatic sinuses Nature Immunology 2005 6:1228-1235 DOI:10.1038/ni1269 PMID:16273098
- Sanna, M. G., Liao, J. Y., Jo, E. J., Alfonso, C., Ahn, M. Y., Peterson, M. S., Webb, B., Lefebvre, S., Chun, J., Gray, N., Rosen, H. Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate Journal of Biological Chemistry 2004 279:13839-13848 DOI:10.1074/jbc.M311743200 PMID:14732717