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PLoS Biology

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Overview

articles

  • Integrative illustration for coronavirus outreach.  18. 2020
  • A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool.  17. 2019
  • NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.  17. 2019
  • Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1.  17. 2019
  • Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.  17. 2019
  • Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala.  17. 2019
  • Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α.  14. 2019
  • Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.  17. 2019
  • HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model.  16. 2018
  • Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.  16. 2018
  • The DEAD-box protein Rok1 orchestrates 40S and 60S ribosome assembly by promoting the release of Rrp5 from pre-40S ribosomes to allow for 60S maturation.  14. 2016
  • LKB1 regulates mitochondria-dependent presynaptic calcium clearance and neurotransmitter release properties at excitatory synapses along cortical axons.  14. 2016
  • Bromodomain proteins contribute to maintenance of bloodstream form stage identity in the African trypanosome.  13. 2015
  • The IRE1 α/XBP1s pathway is essential for the glucose response and protection of β cells.  13:e1002277. 2015
  • The RCSB PDB "molecule of the month": Inspiring a molecular view of biology.  13:e1002140. 2015
  • Modulation of the maladaptive stress response to manage diseases of protein folding.  12. 2014
  • Disentangling human tolerance and resistance against HIV.  12. 2014
  • HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors.  11. 2013
  • Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain.  11. 2013
  • Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription.  11:e1001647. 2013
  • Forty years in the making: Understanding the molecular mechanism of peptide regulation in bacterial development.  11:e1001516. 2013
  • Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides.  10. 2012
  • Functional amyloidogenesis and cytotoxicity: insights into biology and pathology.  10. 2012
  • Bit by bit: The Darwinian basis of life.  10:e1001323. 2012
  • The reality of pervasive transcription.  9:e1000625. 2011
  • Enzymatic blockade of the ubiquitin-proteasome pathway.  9:e1000605. 2011
  • Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of c. Elegans bardet-biedl syndrome mutants.  9:e1001219. 2011
  • High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.  8:e1000559. 2010
  • Melanopsin contributions to irradiance coding in the thalamo-cortical visual system.  8. 2010
  • Emergence of noise-induced oscillations in the central circadian pacemaker.  8:e1000513. 2010
  • Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.  8:e1000483. 2010
  • Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements.  8. 2010
  • mRNA secondary structures fold sequentially but exchange rapidly in vivo.  8:e1000307. 2010
  • Exploration of uncharted regions of the protein universe.  7:e1000205. 2009
  • Cargo and dynamin regulate clathrin-coated pit maturation.  7:e1000057. 2009
  • Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.  7:e1000051. 2009
  • Network features of the mammalian circadian clock.  7. 2009
  • The timing of differentiation of adult hippocampal neurons is crucial for spatial memory.  6:2188-2204. 2008
  • A morning-specific phytohormone gene expression program underlying rhythmic plant growth.  6:1887-1898. 2008
  • A gene wiki for community annotation of gene function.  6:1398-1402. 2008
  • Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon.  6:e116. 2008
  • Darwinian evolution on a chip.  6:e85. 2008
  • In vitro whole-genome analysis identifies a susceptibility locus for HIV-1.  6:319-327. 2008
  • Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis.  6:e26. 2008
  • Specific immunosuppression with inducible Foxp3-transduced polyclonal T cells.  6:2401-2413. 2008
  • Filling in the gaps: Artistic license in education and outreach.  5:2759-2762. 2007
  • Global analysis of posttranslational protein arginylation.  5:2231-2242. 2007
  • The diploid genome sequence of an individual human.  5:2113-2144. 2007
  • Structure of the chloroplast ribosome: novel domains for translation regulation.  5. 2007
  • Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome.  5:932-944. 2007
  • Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome.  5:23-38. 2007
  • The marine viromes of four oceanic regions.  4:2121-2131. 2006
  • A distributed chemosensory circuit for oxygen preference in C. elegans.  4:e274. 2006
  • Plasma membrane is the site of productive HIV-1 particle assembly.  4:2296-2310. 2006
  • Functional amyloid formation within mammalian tissue.  4:100-107. 2006
  • A conserved mechanism for sulfonucleotide reduction.  3:e250. 2005
  • Inhibition of mutation and combating the evolution of antibiotic resistance.  3:1024-1033. 2005
  • Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding.  3:777-789. 2005
  • BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis.  2. 2004
  • Interdependency of brassinosteroid and auxin signaling in Arabidopsis.  2:1460-1471. 2004
  • HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells.  2:e198. 2004
  • Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse.  2:2159-2169. 2004
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Identity

International Standard Serial Number (ISSN)

  • 1544-9173

Electronic International Standard Serial Number (EISSN)

  • 1545-7885

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