recent publications
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academic article
- von Drygalski, A., Bhat, V., Gale, A. J., Burnier, L., Cramer, T. J., Griffin, J. H., Mosnier, L. O. An engineered Factor Va prevents bleeding induced by anticoagulant wt activated protein C PLoS One 2014 9:e104304 DOI:10.1371/journal.pone.0104304 PMID:25127130 PMCID:PMC4134195
- von Drygalski, A., Cramer, T. J., Bhat, V., Griffin, J. H., Gale, A. J., Mosnier, L. O. Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant Journal of Thrombosis and Haemostasis 2014 12:363-372 DOI:10.1111/jth.12489 PMID:24818532 PMCID:PMC4161283
- Cramer, T. J., Gale, A. J. The anticoagulant function of coagulation factor v Thrombosis and Haemostasis 2012 107:15-21 DOI:10.1160/th11-06-0431 PMID:22116556
- Cramer, T. J., Gale, A. J. Function of the activated protein c (apc) autolysis loop in activated fviii inactivation British Journal of Haematology 2011 153:644-654 DOI:10.1111/j.1365-2141.2011.08657.x PMID:21457218 PMCID:PMC3091999
- Cramer, T. J., Griffin, J. H., Gale, A. J. Factor V is an anticoagulant cofactor for activated protein C during inactivation of factor Va Pathophysiology of Haemostasis and Thrombosis 2010 37:17-23 DOI:10.1159/000315141 PMID:20501981 PMCID:PMC2974842
- Gale, A. J., Cramer, T. J., Rozenshteyn, D., Cruz, J. R. Detailed mechanisms of the inactivation of factor viiia by activated protein c in the presence of its cofactors, protein s and factor v Journal of Biological Chemistry 2008 283:16355-16362 DOI:10.1074/jbc.M708985200 PMID:18424440 PMCID:PMC2423237