Total synthesis of (+)-superstolide A

Academic Article

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Overview

authors

• Tortosa, M.
• Yakelis, N. A.
• Roush, William

publication date

• 2008

journal

• Journal of the American Chemical Society  Journal

abstract

• A convergent and highly stereocontrolled synthesis of +-superstolide A (1) has been accomplished. Key steps of this synthesis include the intramolecular Suzuki reaction of 26 and the highly diastereoselective transannular Diels-Alder cyclization of macrocyclic octaene 3.

subject areas

• Cyclization
• Cytotoxins
• Macrolides
• Molecular Conformation
• Stereoisomerism
• Tetrahydronaphthalenes

Identity

International Standard Serial Number (ISSN)

• 0002-7863

Digital Object Identifier (DOI)

• 10.1021/ja710238h

PubMed ID

• 18254629

Additional Document Info

start page

• 2722

end page

• 2723

volume

• 130

issue

• 9