recent publications

• academic article

  • Nicolaou, K. C., King, N. P., Finlay, M. R. V., He, Y., Roschangar, F., Vourloumis, D., Vallberg, H., Sarabia, F., Ninkovic, S., Hepworth, D. Total synthesis of epothilone E and related side-chain modified analogues via a stille coupling based strategy Bioorganic & Medicinal Chemistry  1999 7:665-697  DOI:10.1016/s0968-0896(98)00153-9  PMID:10400321
  • Nicolaou, K. C., Finlay, M. R. V., Ninkovic, S., King, N. P., He, Y., Li, T. H., Sarabia, F., Vourloumis, D. Synthesis and biological properties of C12,13-cyclopropylepothilone a and related epothilones Chemistry & Biology  1998 5:365-372  DOI:10.1016/s1074-5521(98)90070-9  PMID:9662505
  • Nicolaou, K. C., Finlay, M. R. V., Ninkovic, S., Sarabia, F. Total synthesis of 26-hydroxy-epothilone b and related analogs via a macrolactonization based strategy Tetrahedron  1998 54:7127-7166  DOI:10.1016/s0040-4020(98)00352-4
  • Nicolaou, K. C., Sarabia, F., Ninkovic, S., Finlay, M. R. V., Boddy, C. N. C. Probing the ring size of epothilones: Total synthesis of 14 -, 15 -, 17 -, and 18 epothilones a Angewandte Chemie-International Edition  1998 37:81-84  DOI:10.1002/(sici)1521-3773(19980202)37:1/2<81::aid-anie81>3.3.co;2-3
  • Nicolaou, K. C., Ninkovic, S., Finlay, M. R. V., Sarabia, F., Li, T. H. Total synthesis of 26-hydroxyepothilone b and related analogues Chemical Communications  1997 2343-2344  DOI:10.1039/a705845d
  • Nicolaou, K. C., Sarabia, F., Finlay, M. R. V., Ninkovic, S., King, N. P., Vourloumis, D., He, Y. Total synthesis of oxazole- and cyclopropane-containing epothilone b analogues by the macrolactonization approach Chemistry-a European Journal  1997 3:1971-1986  DOI:10.1002/chem.19970031212
  • Nicolaou, K. C.*, He, Y.*, Vourloumis, D., Vallberg, H., Roschangar, F., Sarabia, F., Ninkovic, S., Yang, Z., Trujillo, J. I. The olefin metathesis approach to epothilone a and its analogues Journal of the American Chemical Society  1997 119:7960-7973  DOI:10.1021/ja971109i (* = equal contribution)
  • Nicolaou, K. C., Ninkovic, S., Sarabia, F., Vourloumis, D., He, Y., Vallberg, H., Finlay, M. R. V., Yang, Z. Total syntheses of epothilones A and B via a macrolactonization-based strategy Journal of the American Chemical Society  1997 119:7974-7991  DOI:10.1021/ja971110h
  • Nicolaou, K. C., Vourloumis, D., Li, T. H., Pastor, J., Winssinger, N., He, Y., Ninkovic, S., Sarabia, F., Vallberg, H., Roschangar, F., King, N. P., Finlay, M. R. V., et al. Designed epothilones: Combinatorial synthesis, tubulin assembly properties, and cytotoxic action against taxol-resistant tumor cells Angewandte Chemie-International Edition  1997 36:2097-2103  DOI:10.1002/anie.199720971
  • Nicolaou, K. C.*, Winssinger, N.*, Pastor, J., Ninkovic, S., Sarabia, F., He, Y., Vourloumis, D., Yang, Z., Li, T., Giannakakou, P., Hamel, E. Synthesis of epothilones A and B in solid and solution phase Nature  1997 387:268-272  DOI:10.1038/387268a0  PMID:9153390 (* = equal contribution)
  • Nicolaou, K. C., Sarabia, F., Ninkovic, S., Yang, Z. Total synthesis of epothilone a: The macrolactonization approach Angewandte Chemie-International Edition  1997 36:525-527  DOI:10.1002/anie.199705251