recent publications
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academic article
- Nicolaou, K. C., King, N. P., Finlay, M. R. V., He, Y., Roschangar, F., Vourloumis, D., Vallberg, H., Sarabia, F., Ninkovic, S., Hepworth, D. Total synthesis of epothilone E and related side-chain modified analogues via a stille coupling based strategy Bioorganic & Medicinal Chemistry 1999 7:665-697 DOI:10.1016/s0968-0896(98)00153-9 PMID:10400321
- Nicolaou, K. C., Finlay, M. R. V., Ninkovic, S., King, N. P., He, Y., Li, T. H., Sarabia, F., Vourloumis, D. Synthesis and biological properties of C12,13-cyclopropylepothilone a and related epothilones Chemistry & Biology 1998 5:365-372 DOI:10.1016/s1074-5521(98)90070-9 PMID:9662505
- Nicolaou, K. C., Finlay, M. R. V., Ninkovic, S., Sarabia, F. Total synthesis of 26-hydroxy-epothilone b and related analogs via a macrolactonization based strategy Tetrahedron 1998 54:7127-7166 DOI:10.1016/s0040-4020(98)00352-4
- Nicolaou, K. C., Sarabia, F., Ninkovic, S., Finlay, M. R. V., Boddy, C. N. C. Probing the ring size of epothilones: Total synthesis of 14 -, 15 -, 17 -, and 18 epothilones a Angewandte Chemie-International Edition 1998 37:81-84 DOI:10.1002/(sici)1521-3773(19980202)37:1/2<81::aid-anie81>3.3.co;2-3
- Nicolaou, K. C., Ninkovic, S., Finlay, M. R. V., Sarabia, F., Li, T. H. Total synthesis of 26-hydroxyepothilone b and related analogues Chemical Communications 1997 2343-2344 DOI:10.1039/a705845d
- Nicolaou, K. C., Sarabia, F., Finlay, M. R. V., Ninkovic, S., King, N. P., Vourloumis, D., He, Y. Total synthesis of oxazole- and cyclopropane-containing epothilone b analogues by the macrolactonization approach Chemistry-a European Journal 1997 3:1971-1986 DOI:10.1002/chem.19970031212
- Nicolaou, K. C.*, He, Y.*, Vourloumis, D., Vallberg, H., Roschangar, F., Sarabia, F., Ninkovic, S., Yang, Z., Trujillo, J. I. The olefin metathesis approach to epothilone a and its analogues Journal of the American Chemical Society 1997 119:7960-7973 DOI:10.1021/ja971109i (* = equal contribution)
- Nicolaou, K. C., Ninkovic, S., Sarabia, F., Vourloumis, D., He, Y., Vallberg, H., Finlay, M. R. V., Yang, Z. Total syntheses of epothilones A and B via a macrolactonization-based strategy Journal of the American Chemical Society 1997 119:7974-7991 DOI:10.1021/ja971110h
- Nicolaou, K. C., Vourloumis, D., Li, T. H., Pastor, J., Winssinger, N., He, Y., Ninkovic, S., Sarabia, F., Vallberg, H., Roschangar, F., King, N. P., Finlay, M. R. V., et al. Designed epothilones: Combinatorial synthesis, tubulin assembly properties, and cytotoxic action against taxol-resistant tumor cells Angewandte Chemie-International Edition 1997 36:2097-2103 DOI:10.1002/anie.199720971
- Nicolaou, K. C.*, Winssinger, N.*, Pastor, J., Ninkovic, S., Sarabia, F., He, Y., Vourloumis, D., Yang, Z., Li, T., Giannakakou, P., Hamel, E. Synthesis of epothilones A and B in solid and solution phase Nature 1997 387:268-272 DOI:10.1038/387268a0 PMID:9153390 (* = equal contribution)
- Nicolaou, K. C., Sarabia, F., Ninkovic, S., Yang, Z. Total synthesis of epothilone a: The macrolactonization approach Angewandte Chemie-International Edition 1997 36:525-527 DOI:10.1002/anie.199705251