recent publications

• academic article

  • Velagapudi, S. P., Seedhouse, S. J., French, J., Disney, M. D. Defining the rna internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis Journal of the American Chemical Society  2011 133:10111-10118  DOI:10.1021/ja200212b  PMID:21604752  PMCID:PMC3126894
  • Seedhouse, S. J., Labuda, L. P., Disney, M. D. The privileged chemical space predictor (PCSP): A computer program that identifies privileged chemical space from screens of modularly assembled chemical libraries Bioorganic & Medicinal Chemistry Letters  2010 20:1338-1343  DOI:10.1016/j.bmcl.2010.01.017  PMID:20097562  PMCID:PMC2825671
  • Velagapudi, S. P., Seedhouse, S. J., Disney, M. D. Structure-activity relationships through sequencing (stARTS) defines optimal and suboptimal RNA motif targets for small molecules Angewandte Chemie-International Edition  2010 49:3816-3818  DOI:10.1002/anie.200907257  PMID:20397174  PMCID:PMC3021749
  • Paul, D. J., Seedhouse, S. J., Disney, M. D. Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside-RNA hairpin loop interactions Nucleic Acids Research  2009 37:5894-5907  DOI:10.1093/nar/gkp594  PMID:19726586  PMCID:PMC2761267