recent publications

• academic article

  • Qiu, J. Z., Liu, R., Chapados, B. R., Sherman, M., Tainer, J. A., Shen, B. H. Interaction interface of human flap endonuclease-1 with its DNA substrates Journal of Biological Chemistry  2004 279:24394-24402  DOI:10.1074/jbc.M401464200  PMID:15037610
  • Chapados, B. R., Hosfield, D. J., Han, S., Qiu, J. Z., Yelent, B., Shen, B. H., Tainer, J. A. Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair Cell  2004 116:39-50  DOI:10.1016/s0092-8674(03)01036-5  PMID:14718165
  • Chapados, B. R., Chai, Q., Hosfield, D. J., Qiu, J. Z., Shen, B. H., Tainer, J. A. Structural biochemistry of a type 2 rnase h: Rna primer recognition and removal during DNA replication Journal of Molecular Biology  2001 307:541-556  DOI:10.1006/jmbi.2001.4494  PMID:11254381
  • Shen, B. H., Qiu, J. Z., Hosfield, D., Tainer, J. A. Flap endonuclease homologs in archaebacteria exist as independent proteins Trends in Biochemical Sciences  1998 23:171-173  DOI:10.1016/s0968-0004(98)01199-2  PMID:9612080