recent publications

• academic article

  • Du, D. G., Murray, A. N., Cohen, E., Kim, H. E., Simkovsky, R., Dillin, A., Kelly, J. W. A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues Biochemistry  2011 50:1607-1617  DOI:10.1021/bi1013744  PMID:21268584  PMCID:PMC3051019
  • Topol, E. J., Bousser, M. G., Fox, K. A. A., Creager, M. A., Despres, J. P., Easton, J. D., Hamm, C. W., Montalescot, G., Steg, P. G., Pearson, T. A., Cohen, E., Gaudin, C., et al. Rimonabant for prevention of cardiovascular events (crescendo): A randomised, multicentre, placebo-controlled trial Lancet  2010 376:517-523  DOI:10.1016/s0140-6736(10)60935-x  PMID:20709233
  • Cohen, E., Du, D. G., Joyce, D., Kapernick, E. A., Volovik, Y., Kelly, J. W., Dillin, A. Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection Aging Cell  2010 9:126-134  DOI:10.1111/j.1474-9726.2009.00541.x  PMID:20003171  PMCID:PMC3026833
  • Bieschke, J., Cohen, E., Murray, A., Dillin, A., Kelly, J. W. A kinetic assessment of the C. elegans amyloid disaggregation activity enables uncoupling of disassembly and proteolysis Protein Science  2009 18:2231-2241  DOI:10.1002/pro.234  PMID:19701939  PMCID:PMC2788278
  • Cohen, E., Paulsson, J. F., Blinder, P., Burstyn-Cohen, T., Du, D. G., Estepa, G., Adame, A., Pham, H. M., Holzenberger, M., Kelly, J. W., Masliah, E., Dillin, A. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice Cell  2009 139:1157-1169  DOI:10.1016/j.cell.2009.11.014  PMID:20005808  PMCID:PMC3017511
  • Cohen, E., Bieschke, J., Perciavalle, R. M., Kelly, J. W., Dillin, A. Opposing activities protect against age-onset proteotoxicity Science  2006 313:1604-1610  DOI:10.1126/science.1124646  PMID:16902091
  • Topol, E. J., Mark, D. B., Lincoff, A. M., Cohen, E., Burton, J., Kleiman, N., Talley, D., Sapp, S., Booth, J., Cabot, C. F., Anderson, K. M., Califf, R. M., et al. Outcomes at 1 year and economic implications of platelet glycoprotein iib/iiia blockade in patients undergoing coronary stenting: Results from a multicentre randomised trial Lancet  1999 354:2019-2024  DOI:10.1016/s0140-6736(99)10018-7  PMID:10636365
  • Topol, E. J., Lincoff, A. M., Califf, R. M., Tcheng, J. E., Kleiman, N. S., Adelman, A. G., Burton, J. R., Talley, J. D., Ivanhoe, R. J., Ducas, C., Cheung, P. K., Schick, U., et al. Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade Lancet  1998 352:87-92  DOI:10.1016/s0140-6736(98)85010-1  PMID:9672272
  • Pichard, A., Ivanhoe, R., Satler, L., Masden, R., Chapekis, A., Lee, K. L., Reen, B., Levine, G., Abbottsmith, C., Gottlieb, R. S., Stillabower, M., Chambers, J., et al. A multicenter, randomized trial of coronary angioplasty versus directional atherectomy for patients with saphenous vein bypass graft lesions Circulation  1995 91:1966-1974  PMID:7895354