Promiscuous Watson-Crick cross-pairing within the family of pentopyranosyl (4 '-> 2 ') oligonucleotides

Academic Article
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publication date

  • November 1999

abstract

  • [formula: see text] The D-beta-ribo, D-beta-xylo, L-alpha-lyxo, and L-alpha-arabino members of the pentopyranosyl (4'-->2') oligonucleotide family show efficient intersystem cross-pairing among each other. This family of configurationally isomeric and conformationally well-defined pairing systems offers an opportunity to study structural factors that determine cross-communication between informational oligonucleotide systems of different backbone structure.