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Promiscuous Watson-Crick cross-pairing within the family of pentopyranosyl (4 '-> 2 ') oligonucleotides

Academic Article
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Overview

authors

  • Jungmann, O.
  • Wippo, H.
  • Stanek, M.
  • Huynh, H. K.
  • Krishnamurthy, Ramanarayanan
  • Eschenmoser, A.

publication date

  • November 1999

journal

  • Organic Letters  Journal

abstract

  • [formula: see text] The D-beta-ribo, D-beta-xylo, L-alpha-lyxo, and L-alpha-arabino members of the pentopyranosyl (4'-->2') oligonucleotide family show efficient intersystem cross-pairing among each other. This family of configurationally isomeric and conformationally well-defined pairing systems offers an opportunity to study structural factors that determine cross-communication between informational oligonucleotide systems of different backbone structure.

subject areas

  • Base Pairing
  • Nucleic Acid Conformation
  • Oligonucleotides
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Identity

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol990183y

PubMed ID

  • 10836019
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Additional Document Info

start page

  • 1527

end page

  • 1530

volume

  • 1

issue

  • 10

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