recent publications

• academic article

  • Li, J., Tumanut, C., Gavigan, J. A., Huang, W. J., Hampton, E. N., Tumanut, R., Suen, K. F., Trauger, J. W., Spraggon, G., Lesley, S. A., Liau, G., Yowe, D., et al. Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity Biochemical Journal  2007 406:203-207  DOI:10.1042/bj20070664  PMID:17608623
  • Trauger, J. W., Jiang, A., Stearns, B. A., LoGrasso, P. V. Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type iii (akrlc2) Biochemistry  2002 41:13451-13459  DOI:10.1021/bi026109w  PMID:12416991
  • Turner, M. S., Lin, F. F., Trauger, J. W., Stephens, J., LoGrasso, P. Characterization and purification of truncated human rho-kinase ii expressed in sf-21 cells Archives of Biochemistry and Biophysics  2002 405:13-20  DOI:10.1016/s0003-9861(02)00249-7  PMID:12176052
  • Trauger, J. W., Lin, F. F., Turner, M. S., Stephens, J., LoGrasso, P. V. Kinetic mechanism for human rho-kinase ii (rock-ii) Biochemistry  2002 41:8948-8953  DOI:10.1021/bi0258243  PMID:12102637
  • Dickinson, L. A., Trauger, J. W., Baird, E. E., Ghazal, P., Dervan, P. B., Gottesfeld, J. M. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides Biochemistry  1999 38:10801-10807  DOI:10.1021/bi9912847  PMID:10451376
  • Dickinson, L. A., Trauger, J. W., Baird, E. E., Dervan, P. B., Graves, B. J., Gottesfeld, J. M. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappa B, and DNA by a designed DNA-binding ligand Journal of Biological Chemistry  1999 274:12765-12773  DOI:10.1074/jbc.274.18.12765  PMID:10212261
  • McBryant, S. J., Baird, E. E., Trauger, J. W., Dervan, P. B., Gottesfeld, J. M. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand Journal of Molecular Biology  1999 286:973-981  DOI:10.1006/jmbi.1999.2539  PMID:10047474
  • Dickinson, L. A., Gulizia, R. J., Trauger, J. W., Baird, E. E., Mosier, D. E., Gottesfeld, J. M., Dervan, P. B. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands Proceedings of the National Academy of Sciences of the United States of America  1998 95:12890-12895  DOI:10.1073/pnas.95.22.12890  PMID:9789010  PMCID:PMC23643
  • Neely, L., Trauger, J. W., Baird, E. E., Dervan, P. B., Gottesfeld, J. M. Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex Journal of Molecular Biology  1997 274:439-445  DOI:10.1006/jmbi.1997.1411  PMID:9417925
  • Gottesfeld, J. M., Neely, L., Trauger, J. W., Baird, E. E., Dervan, P. B. Regulation of gene expression by small molecules Nature  1997 387:202-205  DOI:10.1038/387202a0  PMID:9144294