recent publications

• academic article

  • Kamenecka, T. M., Park, Y. J., Lin, L. S., de Laszlo, S., McCauley, E. D., Van Riper, G., Egger, L., Kidambi, U., Mumford, R. A., Tong, S., Tang, W., Colletti, A., et al. Amidines as amide bond replacements in VLA-4 antagonists Bioorganic & Medicinal Chemistry Letters  2004 14:2323-2326  DOI:10.1016/j.bmcl.2004.01.100  PMID:15081033
  • Lin, L. S., Lanza, T. J., Castonguay, L. A., Kamenecka, T., McCauley, E., Van Riper, G., Egger, L. A., Mumford, R. A., Tong, X. C., MacCoss, M., Schmidt, J. A., Hagmann, W. K. Bioisosteric replacement of anilide with benzoxazole: Potent and orally bioavailable antagonists of VLA-4 Bioorganic & Medicinal Chemistry Letters  2004 14:2331-2334  DOI:10.1016/j.bmcl.2004.01.098  PMID:15081035
  • Li, B., de Laszlo, S. E., Kamenecka, T. M., Kopka, I. E., Durette, P. L., Lanza, T., MacCoss, M., Tong, S., Mumford, R. A., McCauley, E. D., Van Riper, G., Schmidt, J. A., et al. N-(arylacetyl)-biphenylalanines as potent vla-4 antagonists Bioorganic & Medicinal Chemistry Letters  2002 12:2141-2144  DOI:10.1016/s0960-894x(02)00366-9  PMID:12127523
  • Kamenecka, T. M., Lanza, T., de Laszlo, S. E., Li, B., McCauley, E. D., Van Riper, G., Egger, L. A., Kidambi, U., Mumford, R. A., Tong, S., MacCoss, M., Schmidt, J. A., et al. N-aryl-prolyl-dipeptides as potent antagonists of VLA-4 Bioorganic & Medicinal Chemistry Letters  2002 12:2205-2208  DOI:10.1016/s0960-894x(02)00356-6  PMID:12127538
  • Lin, L. S., Kopka, I. E., Mumford, R. A., Magriotis, P. A., Lanza, T., Durette, P. L., Kamenecka, T., Young, D. N., de Laszlo, S. E., McCauley, E., Van Riper, G., Kidambi, U., et al. The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists Bioorganic & Medicinal Chemistry Letters  2002 12:611-614  DOI:10.1016/s0960-894x(01)00818-6  PMID:11844683
  • Hagmann, W. K., Durette, P. L., Lanza, T., Kevin, N. J., de Laszlo, S. E., Kopka, H. E., Young, D., Magriotis, P. A., Li, B., Lin, L. S., Yang, G., Kamenecka, T., et al. The discovery of sulfonylated dipeptides as potent VLA-4 antagonists Bioorganic & Medicinal Chemistry Letters  2001 11:2709-2713  DOI:10.1016/s0960-894x(01)00544-3  PMID:11591507
  • Calaycay, J. R., Kelly, T. M., MacNaul, K. L., McCauley, E. D., Qi, H. B., Grant, S. K., Griffin, P. R., Klatt, T., Raju, S. M., Nussler, A. K., Shah, S., Weidner, J. R., et al. Expression and immunoaffinity purification of human inducible nitric-oxide synthase - inhibition studies with 2-amino-5,6-dihydro-4H-1,3-thiazine Journal of Biological Chemistry  1996 271:28212-28219  PMID:8910438
  • Howard, A. D., Palyha, O. C., Griffin, P. R., Peterson, E. P., Lenny, A. B., Ding, G. J. F., Pickup, D. J., Thornberry, N. A., Schmidt, J. A., Tocci, M. J. Human IL-1-beta processing and secretion in recombinant baculovirus-infected Sf9 cells is blocked by the cowpox virus serpin crmA Journal of Immunology  1995 154:2321-2332  PMID:7868902