Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
As of April 1st VIVO Scientific Profiles will no longer updated for faculty, and the link to VIVO will be removed from the library website. Faculty profile pages will continue to be updated via Interfolio. VIVO will continue being used behind the scenes to update graduate student profiles. Please contact helplib@scripps.edu if you have questions.
How to download citations from VIVO | Alternative profile options

Evidence that dynamin-2 functions as a signal-transducing gtpase

Academic Article
uri icon
  • Overview
  • Research
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Fish, K. N.
  • Schmid, Sandra
  • Damke, H.

publication date

  • July 2000

journal

  • Journal of Cell Biology  Journal

abstract

  • The role of dynamin GTPases in the regulation of receptor-mediated endocytosis is well established. Here, we present new evidence that the ubiquitously expressed isoform dynamin-2 (dyn2) can also function in a signal transduction pathway(s). A 200-fold overexpression of dyn1, the 70% identical neuronal isoform, has no effect. Our data suggest that dyn2 can act as a signal transducing GTPase affecting transcriptional regulation.

subject areas

  • Adenoviridae
  • Apoptosis
  • Cell Division
  • Cell Survival
  • Dynamin I
  • Dynamins
  • GTP Phosphohydrolases
  • Genetic Vectors
  • Guanosine Triphosphate
  • HeLa Cells
  • Humans
  • Protein Isoforms
  • Protein Synthesis Inhibitors
  • Signal Transduction
  • Tetracycline
  • Transfection
  • Tumor Suppressor Protein p53
  • Ubiquitins
scroll to property group menus

Research

keywords

  • GTPase
  • apoptosis
  • dynamin
  • endocytosis
  • p53
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0021-9525

Digital Object Identifier (DOI)

  • 10.1083/jcb.150.1.145

PubMed ID

  • 10893263
scroll to property group menus

Additional Document Info

start page

  • 145

end page

  • 154

volume

  • 150

issue

  • 1

©2022 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support