recent publications

• academic article

  • Kojetin, D. J., Thompson, R. J., Benson, L. M., Naylor, S., Waterman, J., Davies, K. G., Opperman, C. H., Stephenson, K., Hoch, J. A., Cavanagh, J. Structural analysis of divalent metals binding to the bacillus subtilis response regulator spo0f: The possibility for in vitro metalloregulation in the initiation of sporulation Biometals  2005 18:449-466  DOI:10.1007/s10534-005-4303-8  PMID:16333746
  • Stephenson, K., Hoch, J. A. Developing inhibitors to selectively target two-component and phosphorelay signal transduction systems of pathogenic microorganisms Current Medicinal Chemistry  2004 11:765-773  DOI:10.2174/0929867043455765  PMID:15032730
  • Stephenson, K., Hoch, J. A. Evolution of signalling in the sporulation phosphorelay Molecular Microbiology  2002 46:297-304  DOI:10.1046/j.1365-2958.2002.03186.x  PMID:12406209
  • Stephenson, K., Hoch, J. A. Two-component and phosphorelay signal-transduction systems as therapeutic targets Current Opinion in Pharmacology  2002 2:507-512  DOI:10.1016/s1471-4892(02)00194-7  PMID:12324251
  • Stephenson, K., Hoch, J. A. Virulence- and antibiotic resistance-associated two-component signal transduction systems of gram-positive pathogenic bacteria as targets for antimicrobial therapy Pharmacology & Therapeutics  2002 93:293-305  DOI:10.1016/s0163-7258(02)00198-5  PMID:12191621
  • Stephenson, K., Hoch, J. A. Pas-a domain of phosphorelay sensor kinase a: A catalytic atp-binding domain involved in the initiation of development in bacillus subtilis Proceedings of the National Academy of Sciences of the United States of America  2001 98:15251-15256  DOI:10.1073/pnas.251408398  PMID:11734624  PMCID:PMC65015
  • Wang, L., Fabret, C., Kanamaru, K., Stephenson, K., Dartois, V., Perego, M., Hoch, J. A. Dissection of the functional and structural domains of phosphorelay histidine kinase a of bacillus subtilis Journal of Bacteriology  2001 183:2795-2802  DOI:10.1128/jb.183.9.2795-2802.2001  PMID:11292798
  • Stephenson, K., Yamaguchi, Y., Hoch, J. A. The mechanism of action of inhibitors of bacterial two-component signal transduction systems Journal of Biological Chemistry  2000 275:38900-38904  DOI:10.1074/jbc.M006633200  PMID:10978341