recent publications

• academic article

  • Nawrocki, S. T., Carew, J. S., Maclean, K. H., Courage, J. F., Huang, P., Houghton, J. A., Cleveland, J. L., Giles, F. J., McConkey, D. J. Myc regulates aggresome formation, the induction of noxa, and apoptosis in response to the combination of bortezomib and saha Blood  2008 112:2917-2926  DOI:10.1182/blood-2007-12-130823  PMID:18641367  PMCID:PMC2556625
  • Maclean, K. H., Dorsey, F. C., Cleveland, J. L., Kastan, M. B. Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis Journal of Clinical Investigation  2008 118:79-88  DOI:10.1172/jci33700  PMID:18097482  PMCID:PMC2148253
  • Maclean, K. H., Kastan, M. B., Cleveland, J. L. Atm deficiency affects both apoptosis and proliferation to augment myc-induced lymphomagenesis Molecular Cancer Research  2007 5:705-711  DOI:10.1158/1541-7786.mcr-07-0058  PMID:17634425
  • Keller, U., Nilsson, J. A., Maclean, K. H., Old, J. B., Cleveland, J. L. Nfkb1 is dispensable for myc-induced lymphomagenesis Oncogene  2005 24:6231-6240  DOI:10.1038/sj.onc.1208779  PMID:15940251
  • Ulett, G. C., Maclean, K. H., Nekkalapu, S., Cleveland, J. L., Adderson, E. E. Mechanisms of group b streptococcal-induced apoptosis of murine macrophages Journal of Immunology  2005 175:2555-2562  PMID:16081829
  • Nilsson, J. A., Maclean, K. H., Keller, U. B., Pendeville, H., Baudino, T. A., Cleveland, J. L. Mnt loss triggers myc transcription targets, proliferation, apoptosis, and transformation Molecular and Cellular Biology  2004 24:1560-1569  DOI:10.1128/mcb.24.4.1560-1569.2004  PMID:14749372
  • Maclean, K. H., Keller, U. B., Rodriguez-Galindo, C., Nilsson, J. A., Cleveland, J. L. C-myc augments gamma irradiation-induced apoptosis by suppressing bcl-x-l Molecular and Cellular Biology  2003 23:7256-7270  DOI:10.1128/mcb.23.20.7256-7270.2003  PMID:14517295
  • Baudino, T. A., Maclean, K. H., Brennan, J., Parganas, E., Yang, C. Y., Aslanian, A., Lees, J. A., Sherr, C. J., Roussel, M. F., Cleveland, J. L. Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by e2f1 loss Molecular Cell  2003 11:905-914  DOI:10.1016/s1097-2765(03)00102-3  PMID:12718877
  • Baudino, T. A., McKay, C., Pendeville-Samain, H., Nilsson, J. A., Maclean, K. H., White, E. L., Davis, A. C., Ihle, J. N., Cleveland, J. L. C-myc is essential for vasculogenesis and angiogenesis during development and tumor progression Genes & Development  2002 16:2530-2543  DOI:10.1101/gad.1024602  PMID:12368264  PMCID:PMC187450
  • Maclean, K. H., Cleveland, J. L., Porter, J. B. Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes Blood  2001 98:3831-3839  DOI:10.1182/blood.V98.13.3831  PMID:11739193