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Receptor-based assays

Academic Article
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Overview

authors

  • Strosberg, Donny
  • Leysen, J. E.

publication date

  • February 1991

journal

  • Current Opinion in Biotechnology  Journal

abstract

  • Receptor-based assays have benefitted from the newest advances in biotechnology and electronics in three main ways: genetically engineered cells expressing single receptor subtypes have been developed for many natural and synthetic ligands; assays have been designed which take advantage of a variety of signals triggered in cells by binding, or inhibition of binding, of ligands to surface-bound receptors; and radiolabelled ligand assays have been considerably improved and simplified by novel electronic devices.

subject areas

  • Animals
  • Beta Particles
  • Filtration
  • Humans
  • Ligands
  • Phosphorylation
  • Receptors, Cell Surface
  • Tyrosine
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Identity

International Standard Serial Number (ISSN)

  • 0958-1669

Digital Object Identifier (DOI)

  • 10.1016/0958-1669(91)90058-d

PubMed ID

  • 1369349
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Additional Document Info

start page

  • 30

end page

  • 36

volume

  • 2

issue

  • 1

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