recent publications
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academic article
- Wieland, S., Makowska, Z., Campana, B., Calabrese, D., Dill, M. T., Chung, J., Chisari, F. V., Heim, M. H. Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver Hepatology 2014 59:2121-2130 DOI:10.1002/hep.26770 PMID:24122862 PMCID:PMC3975814
- Ki, M. K., Jeoung, M. H., Choi, J. R., Rho, S. S., Kwon, Y. G., Shim, H., Chung, J., Hong, H. J., Song, B. D., Lee, S. Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro Oncogene 2013 32:5449-5457 DOI:10.1038/onc.2013.156 PMID:23644659 PMCID:PMC3898107
- Isogawa, M., Chung, J., Murata, Y., Kakimi, K., Chisari, F. V. CD40 activation rescues antiviral CD8+ T cells from PD-1-mediated exhaustion PLoS Pathogens 2013 9:e1003490 DOI:10.1371/journal.ppat.1003490 PMID:23853599 PMCID:PMC3708877
- Friesland, M., Mingorance, L., Chung, J., Chisari, F. V., Gastaminza, P. Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection Journal of Virology 2013 87:6377-6390 DOI:10.1128/jvi.03557-12 PMID:23536676 PMCID:PMC3648129
- Dreux, M., Garaigorta, U., Boyd, B., Decembre, E., Chung, J., Whitten-Bauer, C., Wieland, S., Chisari, F. V. Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity Cell Host & Microbe 2012 12:558-570 DOI:10.1016/j.chom.2012.08.010 PMID:23084922 PMCID:PMC3479672
- Gastaminza, P., Pitram, S. M., Dreux, M., Krasnova, L. B., Whitten-Bauer, C., Dong, J. J., Chung, J., Fokin, V. V., Sharpless, K. B., Chisari, F. V. Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection Journal of Virology 2011 85:5513-5523 DOI:10.1128/jvi.02116-10 PMID:21430055 PMCID:PMC3094966
- Yang, P. L., Althage, A., Chung, J., Maier, H., Wieland, S., Isogawa, M., Chisari, F. V. Immune effectors required for hepatitis B virus clearance Proceedings of the National Academy of Sciences of the United States of America 2010 107:798-802 DOI:10.1073/pnas.0913498107 PMID:20080755 PMCID:PMC2818933
- Lee, S., Chung, J., Ha, I. S., Yi, K., Lee, J. E., Kang, H. G., Choi, I., Oh, K. H., Kim, J. Y., Surh, C. D., Ahn, C. Hydrogen peroxide increases human leukocyte adhesion to porcine aortic endothelial cells via nf kappa b-dependent up-regulation of vcam-1 International Immunology 2007 19:1349-1359 DOI:10.1093/intimm/dxm104 PMID:17977815
- Cheng, G. F., Zhong, J., Chung, J., Chisari, F. V. Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells Proceedings of the National Academy of Sciences of the United States of America 2007 104:9035-9040 DOI:10.1073/pnas.0703285104 PMID:17517627 PMCID:PMC1885623
- Zhong, J., Gastaminza, P., Chung, J., Stamataki, Z., Isogawa, M., Cheng, G. F., McKeating, J. A., Chisari, F. V. Persistent hepatitis C virus infection in vitro: Coevolution of virus and host Journal of Virology 2006 80:11082-11093 DOI:10.1128/jvi.01307-06 PMID:16956932
- Uprichard, S. L., Chung, J., Chisari, F. V., Wakita, T. Replication of a hepatitis C virus replicon clone in mouse cells Virology Journal 2006 3:89 DOI:10.1186/1743-422x-3-89 PMID:17069661
- Sidney, J., Asabe, S., Peters, B., Purton, K. A., Chung, J., Pencille, T. J., Purcell, R., Walker, C. M., Chisari, F. V., Sette, A. Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules Immunogenetics 2006 58:559-570 DOI:10.1007/s00251-006-0131-4 PMID:16791621
- Kamenecka, T. M., Bonnefous, C., Govek, S., Vernier, J. M., Hutchinson, J., Chung, J., Reyes-Manalo, G., Anderson, J. J. Dipyridyl amines: Potent metabotropic glutamate subtype 5 receptor antagonists Bioorganic & Medicinal Chemistry Letters 2005 15:4350-4353 DOI:10.1016/j.bmcl.2005.06.059 PMID:16039855
- Bonnefous, C., Vernier, J. M., Hutchinson, J. H., Chung, J., Reyes-Manalo, G., Kamenecka, T. Dipyridyl amides: Potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists Bioorganic & Medicinal Chemistry Letters 2005 15:1197-1200 DOI:10.1016/j.bmcl.2004.11.078 PMID:15686941
- Roppe, J. R., Wang, B. W., Huang, D. H., Tehrani, L., Kamenecka, T., Schweiger, E. J., Anderson, J. J., Brodkin, J., Jiang, X. H., Cramer, M., Chung, J., Reyes-Manalo, G., et al. 5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity Bioorganic & Medicinal Chemistry Letters 2004 14:3993-3996 DOI:10.1016/j.bmcl.2004.05.037 PMID:15225713
- Love, J. J., Li, X., Chung, J., Dyson, H. J., Wright, P. E. The lef-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA Biochemistry 2004 43:8725-8734 DOI:10.1021/bi049591m PMID:15236581
- Yang, P. L., Althage, A., Chung, J., Chisari, F. V. Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection Proceedings of the National Academy of Sciences of the United States of America 2002 99:13825-13830 DOI:10.1073/pnas.202398599 PMID:12374864 PMCID:PMC129782
- Demarest, S. J., Chung, J., Dyson, H. J., Wright, P. E. Letter to the editor: Assignment of a 15 kDa protein complex formed between the p160 coactivator ACTR and CREB binding protein Journal of Biomolecular NMR 2002 22:377-378 DOI:10.1023/a:1014988325241 PMID:12018488
- Demarest, S. J., Martinez-Yamout, M., Chung, J., Chen, H. W., Xu, W., Dyson, H. J., Evans, R. M., Wright, P. E. Mutual synergistic folding in recruitment of cbp/p300 by p160 nuclear receptor coactivators Nature 2002 415:549-553 DOI:10.1038/415549a PMID:11823864
- Atkins, A. R., Chung, J., Deechongkit, S. P., Little, E. B., Edelman, G. M., Wright, P. E., Cunningham, B. A., Dyson, H. J. Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding? Journal of Molecular Biology 2001 311:161-172 DOI:10.1006/jmbi.2001.4861 PMID:11469865
- Bai, Y. W., Chung, J., Dyson, H. J., Wright, P. E. Structural and dynamic characterization of an unfolded state of poplar apo-plastocyanin formed under nondenaturing conditions Protein Science 2001 10:1056-1066 DOI:10.1110/ps.00601 PMID:11316886 PMCID:PMC2374208
- Schwarzinger, S., Kroon, G. J. A., Foss, T. R., Chung, J., Wright, P. E., Dyson, H. J. Sequence-dependent correction of random coil NMR chemical shifts Journal of the American Chemical Society 2001 123:2970-2978 DOI:10.1021/ja003760i PMID:11457007
- Yao, J., Chung, J., Eliezer, D., Wright, P. E., Dyson, H. J. NMR structural and dynamic characterization of the acid-unfolded state of apomyoglobin provides insights into the early events in protein folding Biochemistry 2001 40:3561-3571 DOI:10.1021/bi002776i PMID:11297422
- Laity, J. H., Chung, J., Dyson, H. J., Wright, P. E. Alternative splicing of Wilms' tumor suppressor protein modulates DNA binding activity through isoform-specific DNA-induced conformational changes Biochemistry 2000 39:5341-5348 DOI:10.1021/bi9926678 PMID:10820004
- Eliezer, D., Chung, J., Dyson, H. J., Wright, P. E. Native and non-native secondary structure and dynamics in the pH 4 intermediate of apomyoglobin Biochemistry 2000 39:2894-2901 DOI:10.1021/bi992545f PMID:10715109
- Legge, G. B., Kriwacki, R. W., Chung, J., Hommel, U., Ramage, P., Case, D. A., Dyson, H. J., Wright, P. E. NMR solution structure of the inserted domain of human leukocyte function associated antigen-1 Journal of Molecular Biology 2000 295:1251-1264 DOI:10.1006/jmbi.1999.3409 PMID:10653701
- Topol, C. E., Califf, R. M., Simes, R. J., Van de Werf, F., Diaz, R., Paolasso, E., Aylward, P. E., Keech, A., Klein, W., Piegas, L., Tomov, I., Armstrong, P. W., et al. Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomised trial Lancet 2000 355:337-345 PMID:10665552
- Scrofani, S. D. B., Chung, J., Huntley, J. J. A., Benkovic, S. J., Wright, P. E., Dyson, H. J. NMR characterization of the metallo-beta-lactamase from Bacteroides fragilis and its interaction with a tight-binding inhibitor: role of an active-site loop Biochemistry 1999 38:14507-14514 DOI:10.1021/bi990986t PMID:10545172
- Guidotti, L. G., Rochford, R., Chung, J., Shapiro, M., Purcell, R., Chisari, F. V. Viral clearance without destruction of infected cells during acute HBV infection Science 1999 284:825-829 DOI:10.1126/science.284.5415.825 PMID:10221919
- Ishikawa, T., Kono, D., Chung, J., Fowler, P., Theofilopoulos, A., Kakumu, S., Chisari, F. V. Polyclonality and multispecificity of the CTL response to a single viral epitope Journal of Immunology 1998 161:5842-5850 PMID:9834062
- Foster, M. P., Wuttke, D. S., Clemens, K. R., Jahnke, W., Radhakrishnan, I., Tennant, L., Reymond, M., Chung, J., Wright, P. E. Chemical shift as a probe of molecular interfaces: Nmr studies of DNA binding by the three amino-terminal zinc finger domains from transcription factor iiia Journal of Biomolecular NMR 1998 12:51-71 DOI:10.1023/a:1008290631575 PMID:9729788
- Pasquinelli, C., Shoenberger, J. M., Chung, J., Chang, K. M., Guidotti, L. G., Selby, M., Berger, K., Lesniewski, R., Houghton, M., Chisari, F. V. Hepatitis C virus core and E2 protein expression in transgenic mice Hepatology 1997 25:719-727 DOI:10.1002/hep.510250338 PMID:9049225
- Botuyan, M. V., ToyPalmer, A., Chung, J., Blake, R. C., Beroza, P., Case, D. A., Dyson, H. J. NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential Journal of Molecular Biology 1996 263:752-767 DOI:10.1006/jmbi.1996.0613 PMID:8947573