recent publications

• academic article

  • Wieland, S., Makowska, Z., Campana, B., Calabrese, D., Dill, M. T., Chung, J., Chisari, F. V., Heim, M. H. Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver Hepatology  2014 59:2121-2130  DOI:10.1002/hep.26770  PMID:24122862  PMCID:PMC3975814
  • Isogawa, M., Chung, J., Murata, Y., Kakimi, K., Chisari, F. V. CD40 activation rescues antiviral CD8+ T cells from PD-1-mediated exhaustion PLoS Pathogens  2013 9:e1003490  DOI:10.1371/journal.ppat.1003490  PMID:23853599  PMCID:PMC3708877
  • Ki, M. K., Jeoung, M. H., Choi, J. R., Rho, S. S., Kwon, Y. G., Shim, H., Chung, J., Hong, H. J., Song, B. D., Lee, S. Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro Oncogene  2013 32:5449-5457  DOI:10.1038/onc.2013.156  PMID:23644659  PMCID:PMC3898107
  • Friesland, M., Mingorance, L., Chung, J., Chisari, F. V., Gastaminza, P. Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection Journal of Virology  2013 87:6377-6390  DOI:10.1128/jvi.03557-12  PMID:23536676  PMCID:PMC3648129
  • Dreux, M., Garaigorta, U., Boyd, B., Decembre, E., Chung, J., Whitten-Bauer, C., Wieland, S., Chisari, F. V. Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity Cell Host & Microbe  2012 12:558-570  DOI:10.1016/j.chom.2012.08.010  PMID:23084922  PMCID:PMC3479672
  • Gastaminza, P., Pitram, S. M., Dreux, M., Krasnova, L. B., Whitten-Bauer, C., Dong, J. J., Chung, J., Fokin, V. V., Sharpless, K. B., Chisari, F. V. Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection Journal of Virology  2011 85:5513-5523  DOI:10.1128/jvi.02116-10  PMID:21430055  PMCID:PMC3094966
  • Yang, P. L., Althage, A., Chung, J., Maier, H., Wieland, S., Isogawa, M., Chisari, F. V. Immune effectors required for hepatitis B virus clearance Proceedings of the National Academy of Sciences of the United States of America  2010 107:798-802  DOI:10.1073/pnas.0913498107  PMID:20080755  PMCID:PMC2818933
  • Cheng, G. F., Zhong, J., Chung, J., Chisari, F. V. Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells Proceedings of the National Academy of Sciences of the United States of America  2007 104:9035-9040  DOI:10.1073/pnas.0703285104  PMID:17517627  PMCID:PMC1885623
  • Lee, S., Chung, J., Ha, I. S., Yi, K., Lee, J. E., Kang, H. G., Choi, I., Oh, K. H., Kim, J. Y., Surh, C. D., Ahn, C. Hydrogen peroxide increases human leukocyte adhesion to porcine aortic endothelial cells via nf kappa b-dependent up-regulation of vcam-1 International Immunology  2007 19:1349-1359  DOI:10.1093/intimm/dxm104  PMID:17977815
  • Sidney, J., Asabe, S., Peters, B., Purton, K. A., Chung, J., Pencille, T. J., Purcell, R., Walker, C. M., Chisari, F. V., Sette, A. Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules Immunogenetics  2006 58:559-570  DOI:10.1007/s00251-006-0131-4  PMID:16791621
  • Zhong, J., Gastaminza, P., Chung, J., Stamataki, Z., Isogawa, M., Cheng, G. F., McKeating, J. A., Chisari, F. V. Persistent hepatitis C virus infection in vitro: Coevolution of virus and host Journal of Virology  2006 80:11082-11093  DOI:10.1128/jvi.01307-06  PMID:16956932
  • Uprichard, S. L., Chung, J., Chisari, F. V., Wakita, T. Replication of a hepatitis C virus replicon clone in mouse cells Virology Journal  2006 3:89  DOI:10.1186/1743-422x-3-89  PMID:17069661
  • Bonnefous, C., Vernier, J. M., Hutchinson, J. H., Chung, J., Reyes-Manalo, G., Kamenecka, T. Dipyridyl amides: Potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists Bioorganic & Medicinal Chemistry Letters  2005 15:1197-1200  DOI:10.1016/j.bmcl.2004.11.078  PMID:15686941
  • Kamenecka, T. M., Bonnefous, C., Govek, S., Vernier, J. M., Hutchinson, J., Chung, J., Reyes-Manalo, G., Anderson, J. J. Dipyridyl amines: Potent metabotropic glutamate subtype 5 receptor antagonists Bioorganic & Medicinal Chemistry Letters  2005 15:4350-4353  DOI:10.1016/j.bmcl.2005.06.059  PMID:16039855
  • Roppe, J. R., Wang, B. W., Huang, D. H., Tehrani, L., Kamenecka, T., Schweiger, E. J., Anderson, J. J., Brodkin, J., Jiang, X. H., Cramer, M., Chung, J., Reyes-Manalo, G., et al. 5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity Bioorganic & Medicinal Chemistry Letters  2004 14:3993-3996  DOI:10.1016/j.bmcl.2004.05.037  PMID:15225713
  • Love, J. J., Li, X., Chung, J., Dyson, H. J., Wright, P. E. The lef-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA Biochemistry  2004 43:8725-8734  DOI:10.1021/bi049591m  PMID:15236581
  • Yang, P. L., Althage, A., Chung, J., Chisari, F. V. Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection Proceedings of the National Academy of Sciences of the United States of America  2002 99:13825-13830  DOI:10.1073/pnas.202398599  PMID:12374864  PMCID:PMC129782
  • Demarest, S. J., Chung, J., Dyson, H. J., Wright, P. E. Letter to the editor: Assignment of a 15 kDa protein complex formed between the p160 coactivator ACTR and CREB binding protein Journal of Biomolecular NMR  2002 22:377-378  DOI:10.1023/a:1014988325241  PMID:12018488
  • Demarest, S. J., Martinez-Yamout, M., Chung, J., Chen, H. W., Xu, W., Dyson, H. J., Evans, R. M., Wright, P. E. Mutual synergistic folding in recruitment of cbp/p300 by p160 nuclear receptor coactivators Nature  2002 415:549-553  DOI:10.1038/415549a  PMID:11823864
  • Yao, J., Chung, J., Eliezer, D., Wright, P. E., Dyson, H. J. NMR structural and dynamic characterization of the acid-unfolded state of apomyoglobin provides insights into the early events in protein folding Biochemistry  2001 40:3561-3571  DOI:10.1021/bi002776i  PMID:11297422
  • Schwarzinger, S., Kroon, G. J. A., Foss, T. R., Chung, J., Wright, P. E., Dyson, H. J. Sequence-dependent correction of random coil NMR chemical shifts Journal of the American Chemical Society  2001 123:2970-2978  DOI:10.1021/ja003760i  PMID:11457007
  • Atkins, A. R., Chung, J., Deechongkit, S. P., Little, E. B., Edelman, G. M., Wright, P. E., Cunningham, B. A., Dyson, H. J. Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding? Journal of Molecular Biology  2001 311:161-172  DOI:10.1006/jmbi.2001.4861  PMID:11469865
  • Bai, Y. W., Chung, J., Dyson, H. J., Wright, P. E. Structural and dynamic characterization of an unfolded state of poplar apo-plastocyanin formed under nondenaturing conditions Protein Science  2001 10:1056-1066  DOI:10.1110/ps.00601  PMID:11316886  PMCID:PMC2374208
  • Laity, J. H., Chung, J., Dyson, H. J., Wright, P. E. Alternative splicing of Wilms' tumor suppressor protein modulates DNA binding activity through isoform-specific DNA-induced conformational changes Biochemistry  2000 39:5341-5348  DOI:10.1021/bi9926678  PMID:10820004
  • Topol, C. E., Califf, R. M., Simes, R. J., Van de Werf, F., Diaz, R., Paolasso, E., Aylward, P. E., Keech, A., Klein, W., Piegas, L., Tomov, I., Armstrong, P. W., et al. Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomised trial Lancet  2000 355:337-345  PMID:10665552
  • Legge, G. B., Kriwacki, R. W., Chung, J., Hommel, U., Ramage, P., Case, D. A., Dyson, H. J., Wright, P. E. NMR solution structure of the inserted domain of human leukocyte function associated antigen-1 Journal of Molecular Biology  2000 295:1251-1264  DOI:10.1006/jmbi.1999.3409  PMID:10653701
  • Eliezer, D., Chung, J., Dyson, H. J., Wright, P. E. Native and non-native secondary structure and dynamics in the pH 4 intermediate of apomyoglobin Biochemistry  2000 39:2894-2901  DOI:10.1021/bi992545f  PMID:10715109
  • Scrofani, S. D. B., Chung, J., Huntley, J. J. A., Benkovic, S. J., Wright, P. E., Dyson, H. J. NMR characterization of the metallo-beta-lactamase from Bacteroides fragilis and its interaction with a tight-binding inhibitor: role of an active-site loop Biochemistry  1999 38:14507-14514  DOI:10.1021/bi990986t  PMID:10545172
  • Guidotti, L. G., Rochford, R., Chung, J., Shapiro, M., Purcell, R., Chisari, F. V. Viral clearance without destruction of infected cells during acute HBV infection Science  1999 284:825-829  DOI:10.1126/science.284.5415.825  PMID:10221919
  • Foster, M. P., Wuttke, D. S., Clemens, K. R., Jahnke, W., Radhakrishnan, I., Tennant, L., Reymond, M., Chung, J., Wright, P. E. Chemical shift as a probe of molecular interfaces: Nmr studies of DNA binding by the three amino-terminal zinc finger domains from transcription factor iiia Journal of Biomolecular NMR  1998 12:51-71  DOI:10.1023/a:1008290631575  PMID:9729788
  • Ishikawa, T., Kono, D., Chung, J., Fowler, P., Theofilopoulos, A., Kakumu, S., Chisari, F. V. Polyclonality and multispecificity of the CTL response to a single viral epitope Journal of Immunology  1998 161:5842-5850  PMID:9834062
  • Pasquinelli, C., Shoenberger, J. M., Chung, J., Chang, K. M., Guidotti, L. G., Selby, M., Berger, K., Lesniewski, R., Houghton, M., Chisari, F. V. Hepatitis C virus core and E2 protein expression in transgenic mice Hepatology  1997 25:719-727  DOI:10.1002/hep.510250338  PMID:9049225
  • Botuyan, M. V., ToyPalmer, A., Chung, J., Blake, R. C., Beroza, P., Case, D. A., Dyson, H. J. NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential Journal of Molecular Biology  1996 263:752-767  DOI:10.1006/jmbi.1996.0613  PMID:8947573