recent publications

• academic article

  • del Rincon, S. V., Widschwendter, M., Sun, D., Ekholm-Reed, S., Tat, J., Teixeira, L. K., Ellederova, Z., Grolieres, E., Reed, S. I., Spruck, C. Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints Oncogene  2015 34:1961-1967  DOI:10.1038/onc.2014.137  PMID:24858038  PMCID:PMC4245389
  • Liberal, V., Martinsson-Ahlzen, H. S., Liberal, J., Spruck, C. H., Widschwendter, M., McGowan, C. H., Reed, S. I. Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins Proceedings of the National Academy of Sciences of the United States of America  2012 109:2754-2759  DOI:10.1073/pnas.1102434108  PMID:21697511  PMCID:PMC3286935
  • Akhoondi, S., Sun, D., von der Lehr, N., Apostolidou, S., Klotz, K., Maljukova, A., Cepeda, D., Fiegl, H., Dofou, D., Marth, C., Mueller-Holzner, E., Corcoran, M., et al. Fbxw7/hcdc4 is a general tumor suppressor in human cancer Cancer Research  2007 67:9006-9012  DOI:10.1158/0008-5472.can-07-1320  PMID:17909001
  • Spruck, C., Sun, D., Fiegl, H., Marth, C., Mueller-Holzner, E., Goebel, G., Widschwendter, M., Reed, S. I. Detection of low molecular weight derivatives of cyclin e1 is a function of cyclin e1 protein levels in breast cancer Cancer Research  2006 66:7355-7360  DOI:10.1158/0008-5472.can-05-3240  PMID:16849587
  • Hubalek, M. M., Widschwendter, A., Erdel, M., Gschwendtner, A., Fiegl, H. M., Muller, H. M., Goebel, G., Mueller-Holzner, E., Marth, C., Spruck, C. H., Reed, S. I., Widschwendter, M. Cyclin e dysregulation and chromosomal instability in endometrial cancer Oncogene  2004 23:4187-4192  DOI:10.1038/sj.onc.1207560  PMID:15048079
  • Reed, S. E., Spruck, C. H., Sangfelt, O., van Drogen, F., Mueller-Holzner, E., Widschwendter, M., Zetterberg, A. Mutation of hcdc4 leads to cell cycle deregulation of cyclin e in cancer Cancer Research  2004 64:795-800  DOI:10.1158/0008-5472.can-03-3417  PMID:14871801
  • Spruck, C. H., Strohmaier, H., Sangfelt, O., Muller, H. M., Hubalek, M., Muller-Holzner, E., Marth, C., Widschwendter, M., Reed, S. I. Hcdc4 gene mutations in endometrial cancer Cancer Research  2002 62:4535-4539  PMID:12183400