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Production and regulation of gelatinase-b by human t-cells

Academic Article
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Overview

authors

  • Montgomery, A. M. P.
  • Sabzevari, H.
  • Reisfeld, Ralph

publication date

  • April 1993

journal

  • Biochimica et Biophysica Acta  Journal

abstract

  • Here we describe for the first time the production of gelatinase B (MMP 9; 92-kDa type IV collagenase) by human peripheral blood T-lymphocytes. Expression of this enzyme was found to be dependent on the activation status of these T-cells and to be regulated by Interleukin-2.

subject areas

  • Cell Separation
  • Collagen
  • Collagenases
  • Culture Media, Conditioned
  • Gene Expression Regulation, Enzymologic
  • Humans
  • Interleukin-2
  • Lymphocyte Activation
  • Matrix Metalloproteinase 9
  • Phenotype
  • T-Lymphocytes
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Research

keywords

  • GELATINASE-B
  • INTERLEUKIN-2
  • METALLOPROTEINASE
  • T-LYMPHOCYTE
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Identity

International Standard Serial Number (ISSN)

  • 0006-3002

Digital Object Identifier (DOI)

  • 10.1016/0167-4889(93)90054-s

PubMed ID

  • 8471628
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Additional Document Info

start page

  • 265

end page

  • 268

volume

  • 1176

issue

  • 3

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