Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
As of April 1st VIVO Scientific Profiles will no longer updated for faculty, and the link to VIVO will be removed from the library website. Faculty profile pages will continue to be updated via Interfolio. VIVO will continue being used behind the scenes to update graduate student profiles. Please contact helplib@scripps.edu if you have questions.
How to download citations from VIVO | Alternative profile options

Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo 4.3.1 key building blocks

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

related to degree

  • Baran, Phil, Ph.D. in Chemistry, Scripps Research 1997 - 2001
  • Yoon, Won Hyung, Ph.D. in Chemistry, Scripps Research 1996 - 2001
  • He, Yun, Ph.D. in Organic Chemistry, Scripps Research 1995 - 2000

authors

  • Nicolaou, K.C.
  • Jung, J.
  • Yoon, Won Hyung
  • Fong, K. C.
  • Choi, H. S.
  • He, Yun
  • Zhong, Y. L.
  • Baran, Phil

publication date

  • March 2002

journal

  • Journal of the American Chemical Society  Journal

abstract

  • A brief introduction into the chemistry of the CP-molecules is followed by first-generation synthetic sequences toward key building blocks for their total synthesis. Processes for both racemic and enantiomerically enriched bicyclo[4.3.1] ketone 6 or its equivalent are described, and the absolute stereochemistries of the optically enriched intermediates are determined. The efficient route developed to racemic 6 and the ready access to both enantiomers of key building blocks provided the opportunity for the total synthesis of the CP-molecules and determination of their absolute stereochemistry.

subject areas

  • Enzyme Inhibitors
  • Maleic Anhydrides
  • Stereoisomerism
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja012010l

PubMed ID

  • 11878972
scroll to property group menus

Additional Document Info

start page

  • 2183

end page

  • 2189

volume

  • 124

issue

  • 10

©2022 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support