Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction

Academic Article
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publication date

  • November 2005

abstract

  • Asymmetric intramolecular Michael reaction catalyzed by an organocatalyst derived from cysteine has been developed for the synthesis of chiral bicyclo[4.3.0]nonene and cis-disubstituted cyclopentane skeletons with a creation of three or two contiguous chiral centers in good yield with high diastereo- and excellent enantioselectivities.