recent publications
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academic article
- Seki, H., Xue, S., Hixon, M. S., Pellett, S., Remes, M., Johnson, E. A., Janda, K. D. Toward the discovery of dual inhibitors for botulinum neurotoxin A: concomitant targeting of endocytosis and light chain protease activity Chemical Communications 2015 51:6226-6229 DOI:10.1039/c5cc00677e PMID:25759983
- Seki, H., Pellett, S., Silhar, P., Stowe, G. N., Blanco, B., Lardy, M. A., Johnson, E. A., Janda, K. D. Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain Bioorganic & Medicinal Chemistry 2014 22:1208-1217 DOI:10.1016/j.bmc.2013.11.053 PMID:24360826 PMCID:PMC3919520
- Silhar, P., Eubanks, L. M., Seki, H., Pellet, S., Javor, S., Tepp, W. H., Johnson, E. A., Janda, K. D. Targeting botulinum A cellular toxicity: a prodrug approach Journal of Medicinal Chemistry 2013 56:7870-7879 DOI:10.1021/jm400873n PMID:24127873 PMCID:PMC3880648