recent publications

• academic article

  • Sanders, R. W., van Gils, M. J., Derking, R., Sok, D., Ketas, T. J., Burger, J. A., Ozorowski, G., Cupo, A., Simonich, C., Goo, L., Arendt, H., Kim, H. J., et al. HIV-1 neutralizing antibodies induced by native-like envelope trimers Science  2015 349:aac4223  DOI:10.1126/science.aac4223  PMID:26089353  PMCID:PMC4498988
  • Dosenovic, P., von Boehmer, L., Escolano, A., Jardine, J., Freund, N. T., Gitlin, A. D., McGuire, A. T., Kulp, D. W., Oliveira, T., Scharf, L., Pietzsch, J., Gray, M. D., et al. Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice Cell  2015 161:1505-1515  DOI:10.1016/j.cell.2015.06.003  PMID:26091035  PMCID:PMC4604566
  • McCoy, L. E., Falkowska, E., Doores, K. J., Le, K., Sok, D., van Gils, M. J., Euler, Z., Burger, J. A., Seaman, M. S., Sanders, R. W., Schuitemaker, H., Poignard, P., et al. Incomplete neutralization and deviation from sigmoidal neutralization curves for HIV broadly neutralizing monoclonal antibodies PLoS Pathogens  2015 11:e1005110  DOI:10.1371/journal.ppat.1005110  PMID:26267277  PMCID:PMC4534392
  • Hu, J. K., Crampton, J. C., Cupo, A., Ketas, T., van Gils, M. J., Sliepen, K., de Taeye, S. W., Sok, D., Ozorowski, G., Deresa, I., Stanfield, R., Ward, A. B., et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity Journal of Virology  2015 89:10383-10398  DOI:10.1128/jvi.01653-15  PMID:26246566  PMCID:PMC4580201
  • Huang, J., Kang, B. H., Pancera, M., Lee, J. H., Tong, T., Feng, Y., Imamichi, H., Georgiev, I. S., Chuang, G. Y., Druz, A., Doria-Rose, N. A., Laub, L., et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface Nature  2014 515:138-142  DOI:10.1038/nature13601  PMID:25186731  PMCID:PMC4224615
  • Falkowska, E., Le, K. M., Ramos, A., Doores, K. J., Lee, J. H., Blattner, C., Ramirez, A., Derking, R., van Gils, M. J., Liang, C. H., McBride, R., von Bredow, B., et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers Immunity  2014 40:657-668  DOI:10.1016/j.immuni.2014.04.009  PMID:24768347  PMCID:PMC4070425
  • Sok, D., van Gils, M. J., Pauthner, M., Julien, J. P., Saye-Francisco, K. L., Hsueh, J., Briney, B., Lee, J. H., Le, K. M., Lee, P. S., Hua, Y., Seaman, M. S., et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex Proceedings of the National Academy of Sciences of the United States of America  2014 111:17624-17629  DOI:10.1073/pnas.1415789111  PMID:25422458  PMCID:PMC4267403
  • Sanders, R. W., Derking, R., Cupo, A., Julien, J. P., Yasmeen, A., de Val, N., Kim, H. J., Blattner, C., de la Pena, A. T., Korzun, J., Golabek, M., de los Reyes, K., et al. A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies PLoS Pathogens  2013 9:e1003618  DOI:10.1371/journal.ppat.1003618  PMID:24068931  PMCID:PMC3777863