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Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

Academic Article
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Overview

related to degree

  • Alkutkar, Tanwee P, Ph.D. in Structural Biology/Biophysics, Scripps Research 2018 -

authors

  • He, Linling and Chaudhary, Anshul
  • Lin, Xiaotian
  • Sou, Cindy
  • Alkutkar, Tanwee P
  • Kumar, Sonu and Ngo, Timothy
  • Kosviner, Ezra and Ozorowski, Gabriel
  • Stanfield, Robyn
  • Ward, Andrew
  • Wilson, Ian
  • Zhu, Jiang

publication date

  • May 11, 2021

journal

  • Nature Communications  Journal

subject areas

  • Animals
  • Antibodies, Neutralizing
  • Antigens, Viral
  • B-Lymphocytes
  • Crystallography, X-Ray
  • Disease Models, Animal
  • Ebola Vaccines
  • Ebolavirus
  • Epitopes, T-Lymphocyte
  • Female
  • Glycoproteins
  • Hemorrhagic Fever, Ebola
  • Humans
  • Mice
  • Nanoparticles
  • Protein Domains
  • Protein Engineering
  • Protein Multimerization
  • Protein Stability
  • Rabbits
  • T-Lymphocytes, Helper-Inducer
  • Vaccines, Subunit
  • Viral Proteins
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Identity

PubMed Central ID

  • PMC8113551

International Standard Serial Number (ISSN)

  • 2041-1723

Digital Object Identifier (DOI)

  • 10.1038/s41467-021-22867-w

PubMed ID

  • 33976149
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Additional Document Info

volume

  • 12

issue

  • 1

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