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Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue

Academic Article
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Overview

authors

  • Zhang, Y.
  • Zhang, M.
  • Zhang, Yan Jessie

publication date

  • March 2011

journal

  • Biochemical Journal  Journal

subject areas

  • Amino Acid Sequence
  • Animals
  • Carrier Proteins
  • Catalytic Domain
  • Crystallography, X-Ray
  • Drosophila Proteins
  • Drosophila melanogaster
  • Humans
  • Kinetics
  • Models, Molecular
  • Molecular Sequence Data
  • Mutation
  • Oligopeptides
  • Phosphoprotein Phosphatases
  • Phosphorylation
  • Protein Conformation
  • Protein Tyrosine Phosphatases
  • RNA Polymerase II
  • Recombinant Proteins
  • Saccharomyces cerevisiae Proteins
  • Sequence Analysis, Protein
  • mRNA Cleavage and Polyadenylation Factors
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Research

keywords

  • C-terminal domain
  • RNA polymerase II
  • transcription regulation
  • transcription termination
  • tyrosine phosphatase
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Identity

International Standard Serial Number (ISSN)

  • 0264-6021

Digital Object Identifier (DOI)

  • 10.1042/bj20101471

PubMed ID

  • 21204787
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Additional Document Info

start page

  • 435

end page

  • 444

volume

  • 434

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