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Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site

Academic Article
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Overview

related to degree

  • Vanderwal, Chris, Ph.D. in Chemistry, Scripps Research 1998 - 2003

authors

  • Edler, M. C.
  • Buey, R. M.
  • Gussio, R.
  • Marcus, A. I.
  • Vanderwal, Chris
  • Sorensen, Erik J.
  • Diaz, J. F.
  • Giannakakou, P.
  • Ernest, H.

publication date

  • August 2005

journal

  • Biochemistry  Journal

subject areas

  • Animals
  • Antineoplastic Agents
  • Binding Sites
  • Cattle
  • Cell Line, Tumor
  • Female
  • Humans
  • Kinetics
  • Ligands
  • Microtubules
  • Models, Molecular
  • Ovarian Neoplasms
  • Paclitaxel
  • Polycyclic Compounds
  • Protein Conformation
  • Taxoids
  • Thermodynamics
  • Tubulin
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Identity

International Standard Serial Number (ISSN)

  • 0006-2960

Digital Object Identifier (DOI)

  • 10.1021/bi050660m

PubMed ID

  • 16114889
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Additional Document Info

start page

  • 11525

end page

  • 11538

volume

  • 44

issue

  • 34

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