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Genomewide Association study of tacrolimus concentrations in African American kidney transplant recipients identifies multiple CYP3A5 alleles

Academic Article
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Overview

authors

  • Oetting, W. S.
  • Schladt, D. P.
  • Guan, W.
  • Miller, M. B.
  • Remmel, R. P.
  • Dorr, C.
  • Sanghavi, K.
  • Mannon, R. B.
  • Herrera, B.
  • Matas, A. J.
  • Salomon, Daniel
  • Kwok, P. Y.
  • Keating, B. J.
  • Israni, A. K.
  • Jacobson, P. A.
  • DeKAF Investigators

publication date

  • February 2016

journal

  • American Journal of Transplantation  Journal

subject areas

  • Adolescent
  • Adult
  • African Americans
  • Aged
  • Aged, 80 and over
  • Alleles
  • Child
  • Child, Preschool
  • Cytochrome P-450 CYP3A
  • European Continental Ancestry Group
  • Female
  • Follow-Up Studies
  • Genome-Wide Association Study
  • Genotype
  • Glomerular Filtration Rate
  • Graft Rejection
  • Graft Survival
  • Humans
  • Immunosuppressive Agents
  • Infant
  • Infant, Newborn
  • Kidney Failure, Chronic
  • Kidney Function Tests
  • Kidney Transplantation
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide
  • Postoperative Complications
  • Prognosis
  • Risk Factors
  • Tacrolimus
  • Tissue Donors
  • Transplant Recipients
  • Young Adult
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Research

keywords

  • basic (laboratory) research
  • calcineurin inhibitor: tacrolimus
  • gene array
  • genetics
  • genomics
  • immune modulation
  • immunosuppressant
  • immunosuppression
  • microarray
  • molecular biology: DNA
  • molecular biology: single polynucleotide polymorphism
  • science
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Identity

PubMed Central ID

  • PMC4733408

International Standard Serial Number (ISSN)

  • 1600-6135

Digital Object Identifier (DOI)

  • 10.1111/ajt.13495

PubMed ID

  • 26485092
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Additional Document Info

start page

  • 574

end page

  • 582

volume

  • 16

issue

  • 2

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