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Synthesis of pochoxime prodrugs as potent HSP90 inhibitors

Academic Article
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Overview

authors

  • Wang, C.
  • Barluenga, S.
  • Koripelly, G. K.
  • Fontaine, J. G.
  • Chen, R.
  • Yu, J. C.
  • Shen, X.
  • Chabala, J. C.
  • Heck, J. V.
  • Rubenstein, A.
  • Winssinger, Nicolas

publication date

  • 2009

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Administration, Oral
  • Animals
  • Antineoplastic Agents
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • HSP90 Heat-Shock Proteins
  • Humans
  • Macrolides
  • Mice
  • Mice, Inbred ICR
  • Prodrugs
  • Xenograft Model Antitumor Assays
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Research

keywords

  • HSP90
  • Pochoxime
  • Prodrug
  • Radicicol
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2009.04.030

PubMed ID

  • 19410458
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Additional Document Info

start page

  • 3836

end page

  • 3840

volume

  • 19

issue

  • 14

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