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Both the epitope specificity and isotype are important in the antitumor effect of monoclonal antibodies against Her-2/neu antigen

Academic Article
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Overview

authors

  • Kim, K. M.
  • Shin, E. Y.
  • Moon, J. H.
  • Heo, T. H.
  • Lee, Joon Youb
  • Chung, Y.
  • Lee, Y. J.
  • Cho, H. M.
  • Shin, S. U.
  • Kang, C. Y.

publication date

  • December 2002

journal

  • International Journal of Cancer  Journal

subject areas

  • Animals
  • Antibodies, Monoclonal
  • Antibody Formation
  • Antibody-Dependent Cell Cytotoxicity
  • Antigens, Neoplasm
  • Breast Neoplasms
  • Epitopes
  • Female
  • Flow Cytometry
  • Humans
  • Immunoglobulin Isotypes
  • In Vitro Techniques
  • Mice
  • Mice, Inbred BALB C
  • Neoplasms, Experimental
  • Receptor, ErbB-2
  • Tumor Cells, Cultured
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Research

keywords

  • Her-2/neu
  • anti-tumor effect
  • epitope
  • isotype
  • monoclonal antibody
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Identity

International Standard Serial Number (ISSN)

  • 0020-7136

Digital Object Identifier (DOI)

  • 10.1002/ijc.10732

PubMed ID

  • 12402315
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Additional Document Info

start page

  • 428

end page

  • 434

volume

  • 102

issue

  • 4

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