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Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication

Academic Article
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Overview

authors

  • Garcia, G.
  • Sharma, A.
  • Ramaiah, A.
  • Sen, C.
  • Purkayastha, A.
  • Kohn, D. B.
  • Parcells, M. S.
  • Beck, S.
  • Kim, H.
  • Bakowski, M. A.
  • Kirkpatrick, M. G.
  • Riva, L.
  • Wolff, K. C.
  • Han, B.
  • Yuen, C.
  • Ulmert, D.
  • Purbey, P. K.
  • Scumpia, P.
  • Beutler, Nathan Albert
  • Rogers, T. F.
  • Chatterjee, A. K.
  • Gabriel, G.
  • Bartenschlager, R.
  • Gomperts, B.
  • Svendsen, C. N.
  • Betz, U. A. K.
  • Damoiseaux, R. D.
  • Arumugaswami, V.

publication date

  • March 18, 2021

journal

  • Cell Reports  Journal

subject areas

  • A549 Cells
  • Animals
  • Antiviral Agents
  • COVID-19
  • Cercopithecus aethiops
  • DNA Damage
  • Drug Evaluation, Preclinical
  • HEK293 Cells
  • HeLa Cells
  • Humans
  • Isoxazoles
  • MAP Kinase Signaling System
  • Middle East Respiratory Syndrome Coronavirus
  • Pyrazines
  • SARS-CoV-2
  • Vero Cells
  • Virus Replication
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Identity

PubMed Central ID

  • PMC7969873

International Standard Serial Number (ISSN)

  • 2211-1247

Digital Object Identifier (DOI)

  • 10.1016/j.celrep.2021.108940

PubMed ID

  • 33784499
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Additional Document Info

volume

  • 35

issue

  • 1

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