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Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy

Academic Article
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Overview

authors

  • Hutt, D. M.
  • Mishra, S. K.
  • Roth, D. M.
  • Larsen, M. B.
  • Angles, F.
  • Frizzell, R. A.
  • Balch, William E.

publication date

  • 2018

journal

  • Journal of Biological Chemistry  Journal
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Research

keywords

  • 70 kilodalton heat shock protein (Hsp70)
  • BAG3
  • BCL2-associated athanogene
  • autophagy
  • cystic fibrosis
  • cystic fibrosis transmembrane conductance regulator (CFTR)
  • maladaptive stress response
  • protein folding
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Identity

PubMed Central ID

  • PMC6120199

International Standard Serial Number (ISSN)

  • 0021-9258

Digital Object Identifier (DOI)

  • 10.1074/jbc.RA118.002607

PubMed ID

  • 29986884
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Additional Document Info

start page

  • 13682

end page

  • 13695

volume

  • 293

issue

  • 35

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