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Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK)

Academic Article
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  • Additional Document Info
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Overview

authors

  • Martinez-Botella, G.
  • Breen, J. N.
  • Duffy, J. E. S.
  • Dumas, J.
  • Geng, B. L.
  • Gowers, I. K.
  • Green, O. M.
  • Guler, S.
  • Hentemann, M. F.
  • Hernandez-Juan, F. A.
  • Joseph-McCarthy, D.
  • Kawatkar, S.
  • Larsen, Nicholas
  • Lazari, O.
  • Loch, J. T.
  • Macritchie, J. A.
  • McKenzie, A. R.
  • Newman, J. V.
  • Olivier, N. B.
  • Otterson, L. G.
  • Owens, A. P.
  • Read, J.
  • Sheppard, D. W.
  • Keating, T. A.

publication date

  • November 2012

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Anti-Bacterial Agents
  • Benzoates
  • Catalytic Domain
  • Crystallography, X-Ray
  • Enterococcus
  • Humans
  • Methicillin-Resistant Staphylococcus aureus
  • Microbial Sensitivity Tests
  • Models, Molecular
  • Molecular Structure
  • Nucleoside-Phosphate Kinase
  • Staphylococcus aureus
  • Streptococcus pneumoniae
  • Structure-Activity Relationship
  • Thymine
  • Vancomycin Resistance
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm3011806

PubMed ID

  • 23043329
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Additional Document Info

start page

  • 10010

end page

  • 10021

volume

  • 55

issue

  • 22

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