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N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase

Academic Article
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  • Research
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Overview

authors

  • Mitchell, Michael
  • Son, J. C.
  • Guo, H.
  • Im, Y. A.
  • Cho, E. J.
  • Wang, J.
  • Hayes, J.
  • Wang, M.
  • Paul, A.
  • Lansdon, E. B.
  • Chen, J. M.
  • Graupe, D.
  • Rhodes, G.
  • He, G. X.
  • Geleziunas, R.
  • Xu, L.
  • Kim, C. U.

publication date

  • March 2010

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Animals
  • Anti-HIV Agents
  • Binding Sites
  • Crystallography, X-Ray
  • Dogs
  • HIV Reverse Transcriptase
  • Humans
  • Microsomes
  • Pyrimidinones
  • Reverse Transcriptase Inhibitors
  • Structure-Activity Relationship
  • Thymine
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Research

keywords

  • Human immunodeficiency virus
  • Non-nucleoside
  • Pyrimidinedione
  • Reverse transcriptase
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2010.01.085

PubMed ID

  • 20138513
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Additional Document Info

start page

  • 1589

end page

  • 1592

volume

  • 20

issue

  • 5

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