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Discovery of NVP-LDE225, a potent and selective Smoothened antagonist

Academic Article
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  • Research
  • Identity
  • Additional Document Info
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Overview

authors

  • Pan, S.
  • Wu, Xu
  • Jiang, J.
  • Gao, W.
  • Wan, Y.
  • Cheng, D.
  • Han, D.
  • Liu, J.
  • Englund, N. P.
  • Wang, Y.
  • Peukert, S.
  • Miller-Moslin, K.
  • Yuan, J.
  • Guo, R.
  • Matsumoto, M.
  • Vattay, A.
  • Jiang, Y.
  • Tsao, J.
  • Sun, F.
  • Pferdekamper, A. C.
  • Dodd, S.
  • Tuntland, T.
  • Maniara, W.
  • Kelleher, J. F.
  • Yao, Y. M.
  • Warmuth, M.
  • Williams, J.
  • Dorsch, M.

publication date

  • June 2010

journal

  • ACS Medicinal Chemistry Letters  Journal
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Research

keywords

  • Hedgehog signaling pathway
  • Smoothened
  • medulloblastoma
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Identity

PubMed Central ID

  • PMC4007689

International Standard Serial Number (ISSN)

  • 1948-5875

Digital Object Identifier (DOI)

  • 10.1021/ml1000307

PubMed ID

  • 24900187
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Additional Document Info

start page

  • 130

end page

  • 134

volume

  • 1

issue

  • 3

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