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Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling

Academic Article
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  • Research
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Overview

authors

  • Aboudehen, K.
  • Farahani, S.
  • Kanchwala, M.
  • Chan, S. C.
  • Avdulov, S.
  • Mickelson, A.
  • Lee, D.
  • Gearhart, Micah
  • Patel, V.
  • Xing, C.
  • Igarashi, P.

publication date

  • June 2018

journal

  • Journal of Biological Chemistry  Journal

subject areas

  • Animals
  • Gene Expression Regulation
  • Gene Knockout Techniques
  • Humans
  • Mice
  • Mice, Inbred C57BL
  • Mutation
  • Polycystic Kidney, Autosomal Dominant
  • RNA, Long Noncoding
  • Signal Transduction
  • TOR Serine-Threonine Kinases
  • TRPP Cation Channels
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Research

keywords

  • CRISPR
  • Cas
  • epithelial cell
  • kidney
  • lncRNA)
  • long noncoding RNA (long ncRNA
  • mTOR complex (mTORC)
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Identity

PubMed Central ID

  • PMC6005429

Digital Object Identifier (DOI)

  • 10.1074/jbc.RA118.001723

PubMed ID

  • 29716997
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Additional Document Info

start page

  • 9388

end page

  • 9398

volume

  • 293

issue

  • 24

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