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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

Academic Article
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Overview

related to degree

  • Nazor, Kristopher Lancaster, Ph.D. in Biology, Scripps Research 2008 - 2015

authors

  • Israel, M. A.
  • Yuan, S. H.
  • Bardy, C.
  • Reyna, S. M.
  • Mu, Y.
  • Herrera, C.
  • Hefferan, M. P.
  • Van Gorp, S.
  • Nazor, Kristopher Lancaster
  • Boscolo, F. S.
  • Carson, C. T.
  • Laurent, L. C.
  • Marsala, M.
  • Gage, F. H.
  • Remes, A. M.
  • Koo, E. H.
  • Goldstein, L. S. B.

publication date

  • February 2012

journal

  • Nature  Journal

subject areas

  • Aged, 80 and over
  • Alzheimer Disease
  • Amyloid Precursor Protein Secretases
  • Amyloid beta-Peptides
  • Amyloid beta-Protein Precursor
  • Astrocytes
  • Biomarkers
  • Cells, Cultured
  • Cellular Reprogramming
  • Coculture Techniques
  • Endosomes
  • Enzyme Activation
  • Female
  • Fibroblasts
  • Glycogen Synthase Kinase 3
  • Humans
  • Induced Pluripotent Stem Cells
  • Male
  • Middle Aged
  • Models, Biological
  • Neurons
  • Peptide Fragments
  • Phosphoproteins
  • Phosphorylation
  • Protease Inhibitors
  • Proteolysis
  • Synapsins
  • tau Proteins
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Identity

PubMed Central ID

  • PMC3338985

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/nature10821

PubMed ID

  • 22278060
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Additional Document Info

start page

  • 216

end page

  • 220

volume

  • 482

issue

  • 7384

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