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The X-ray crystal structure of the human mono-oxygenase cytochrome P450 3A5-ritonavir complex reveals active site differences between P450s 3A4 and 3A5

Academic Article
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Overview

authors

  • Hsu, M. H.
  • Savas, U.
  • Johnson, Eric

publication date

  • 2018

journal

  • Molecular Pharmacology  Journal

subject areas

  • Binding Sites
  • Crystallography, X-Ray
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 CYP3A Inhibitors
  • Humans
  • Protein Structure, Secondary
  • Protein Structure, Tertiary
  • Ritonavir
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Identity

PubMed Central ID

  • PMC5708090

International Standard Serial Number (ISSN)

  • 0026-895X

Digital Object Identifier (DOI)

  • 10.1124/mol.117.109744

PubMed ID

  • 29093019
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Additional Document Info

start page

  • 14

end page

  • 24

volume

  • 93

issue

  • 1

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