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Evolution of the active site of human glutathione transferase A2-2 for enhanced activity with dietary isothiocyanates

Academic Article
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Overview

authors

  • Zhang, W.
  • Dourado, Dfar
  • Mannervik, Bengt

publication date

  • April 2015

journal

  • Biochimica Et Biophysica Acta-General Subjects  Journal

subject areas

  • Catalysis
  • Catalytic Domain
  • Diet
  • Glutathione Transferase
  • Humans
  • Isoenzymes
  • Isothiocyanates
  • Substrate Specificity
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Research

keywords

  • Detoxication
  • Directed evolution
  • Enzyme engineering
  • Glutathione transferase
  • Isothiocyanate
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Identity

International Standard Serial Number (ISSN)

  • 0304-4165

Digital Object Identifier (DOI)

  • 10.1016/j.bbagen.2014.12.021

PubMed ID

  • 25542299
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Additional Document Info

start page

  • 742

end page

  • 749

volume

  • 1850

issue

  • 4

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