Structure-based design and discovery of potent and selective KDM5 inhibitors
Academic Article
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Overview
publication date
- 2018
journal
subject areas
- Antineoplastic Agents
- Cell Line, Tumor
- Cell Proliferation
- Dose-Response Relationship, Drug
- Drug Discovery
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors
- Female
- Humans
- Jumonji Domain-Containing Histone Demethylases
- MCF-7 Cells
- Mammary Neoplasms, Experimental
- Models, Molecular
- Molecular Structure
- Nuclear Proteins
- Repressor Proteins
- Retinoblastoma-Binding Protein 2
- Structure-Activity Relationship