Monitoring ligand-induced protein ordering in drug discovery

Academic Article

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• Research
• Identity
• Additional Document Info
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Overview

authors

• Grace, C. R.
• Ban, D.
• Min, J.
• Mayasundari, A.
• Min, L.
• Finch, K. E.
• Griffiths, L.
• Bharatham, N.
• Bashford, D.
• Guy, Rodney Kiplin
• Dyer, M. A.
• Kriwacki, R. W.

publication date

• March 2016

journal

• Journal of Molecular Biology  Journal

subject areas

• Cell Line, Tumor
• Drug Discovery
• Humans
• Imidazoles
• Magnetic Resonance Spectroscopy
• Models, Molecular
• Piperazines
• Protein Binding
• Protein Conformation
• Protein Multimerization
• Proto-Oncogene Proteins c-mdm2
• Structure-Activity Relationship
• Tumor Suppressor Protein p53

Research

keywords

• MdmX
• Nutlin
• drug discovery
• nuclear magnetic resonance
• p53

Identity

PubMed Central ID

• PMC4826315

International Standard Serial Number (ISSN)

• 0022-2836

Digital Object Identifier (DOI)

• 10.1016/j.jmb.2016.01.016

PubMed ID

• 26812210

Additional Document Info

start page

• 1290

end page

• 1303

volume

• 428

issue

• 6