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Discovery of manassantin A protein targets using large-scale protein folding and stability measurements

Academic Article
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Overview

authors

  • Wallace, M. A. G.
  • Kwon, D. Y.
  • Weitzel, D. H.
  • Lee, C. T.
  • Stephenson, T. N.
  • Chi, J. T.
  • Mook Jr., R. A.
  • Dewhirst, M. W.
  • Hong, Jiyong
  • Fitzgerald, M. C.

publication date

  • August 2016

journal

  • Journal of Proteome Research  Journal

subject areas

  • Antineoplastic Agents
  • Biological Products
  • Cells, Cultured
  • Filamins
  • Humans
  • Isotope Labeling
  • Ligands
  • Lignans
  • Oxidation-Reduction
  • Peptide Elongation Factor 1
  • Protein Binding
  • Protein Folding
  • Protein Stability
  • Saururaceae
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Research

keywords

  • Filamin A
  • MDA-MB-231
  • Manassantin A
  • SILAC
  • SPROX
  • cancer
  • chemical denaturation
  • elongation factor 1 alpha
  • iTRAQ
  • mass spectrometry
  • mode-of-action
  • proteomics
  • pulse proteolysis
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Identity

PubMed Central ID

  • PMC5270646

International Standard Serial Number (ISSN)

  • 1535-3893

Digital Object Identifier (DOI)

  • 10.1021/acs.jproteome.6b00237

PubMed ID

  • 27322910
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Additional Document Info

start page

  • 2688

end page

  • 2696

volume

  • 15

issue

  • 8

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