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Enantioselective synthesis of Janus kinase inhibitor INCB018424 via an organocatalytic aza-Michael reaction

Academic Article
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Overview

authors

  • Lin, Q.
  • Meloni, D.
  • Pan, Y.
  • Xia, M.
  • Rodgers, J.
  • Shepard, S.
  • Li, M.
  • Galya, L.
  • Metcalf, B.
  • Yue, T. Y.
  • Liu, P.
  • Zhou, Jiacheng

publication date

  • May 2009

journal

  • Organic Letters  Journal

subject areas

  • Benzoates
  • Catalysis
  • Janus Kinases
  • Molecular Structure
  • Protein Kinase Inhibitors
  • Pyrazoles
  • Stereoisomerism
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Identity

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol900350k

PubMed ID

  • 19385672
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Additional Document Info

start page

  • 1999

end page

  • 2002

volume

  • 11

issue

  • 9

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