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Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ

Academic Article
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Overview

related to degree

  • Suciu, Radu Mihai, Ph.D. in Chemical Biology, Scripps Research 2013 -

authors

  • Lee, H. Y.
  • Suciu, Radu Mihai
  • Horning, B. D.
  • Vinogradova, E. V.
  • Ulanovskaya, O. A.
  • Cravatt, Benjamin

publication date

  • September 2018

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal
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Research

keywords

  • Activity-based profiling
  • Covalent
  • Cysteine
  • Inhibitor
  • Nicotinamide N-methyltransferase
  • Proteomics
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2018.04.017

PubMed ID

  • 29731364
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Additional Document Info

start page

  • 2682

end page

  • 2687

volume

  • 28

issue

  • 16

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