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Novel tricyclic inhibitors of IκB kinase

Academic Article
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  • Additional Document Info
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Overview

authors

  • Kempson, J.
  • Spergel, S. H.
  • Guo, J.
  • Quesnelle, C.
  • Gill, P.
  • Belanger, D.
  • Dyckman, A. J.
  • Li, T.
  • Watterson, S. H.
  • Langevine, C. M.
  • Das, J.
  • Moquin, R. V.
  • Furch, J. A.
  • Marinier, A.
  • Dodier, M.
  • Martel, A.
  • Nirschl, David
  • Van Kirk, K.
  • Burke, J. R.
  • Pattoli, M. A.
  • Gillooly, K.
  • McIntyre, K. W.
  • Chen, L.
  • Yang, Z.
  • Marathe, P. H.
  • Wang-Iverson, D.
  • Dodd, J. H.
  • McKinnon, M.
  • Barrish, J. C.
  • Pitts, W. J.

publication date

  • April 2009

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Animals
  • Crystallography, X-Ray
  • Female
  • Glutathione Transferase
  • Heterocyclic Compounds, 3-Ring
  • Humans
  • I-kappa B Kinase
  • Imidazoles
  • In Vitro Techniques
  • Leukocytes, Mononuclear
  • Lipopolysaccharides
  • Mice
  • Mice, Inbred BALB C
  • Microsomes, Liver
  • Oxazoles
  • Rats
  • Recombinant Fusion Proteins
  • Structure-Activity Relationship
  • Thiazoles
  • Tumor Necrosis Factor-alpha
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm8015816

PubMed ID

  • 19267461
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Additional Document Info

start page

  • 1994

end page

  • 2005

volume

  • 52

issue

  • 7

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