Non-charged thiamine analogs as inhibitors of enzyme transketolase

Academic Article

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• Research
• Identity
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Overview

authors

• Thomas, Allen
• De Meese, J.
• Le Huerou, Y.
• Boyd, S. A.
• Romoff, T. T.
• Gonzales, S. S.
• Gunawardana, I.
• Kaplan, T.
• Sullivan, F.
• Condroski, K.
• Lyssikatos, J. P.
• Aicher, T. D.
• Ballard, J.
• Bernat, B.
• DeWolf, W.
• Han, M.
• Lemieux, C.
• Smith, D.
• Weiler, S.
• Wright, S. K.
• Vigers, G.
• Brandhuber, B.

publication date

• January 2008

journal

• Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

• Animals
• Catalysis
• Cell Line
• Crystallography, X-Ray
• Enzyme Inhibitors
• Humans
• Mice
• Protein Conformation
• Structure-Activity Relationship
• Thiamine
• Transketolase

Research

keywords

• deazathiamine
• pyrazolothiamine
• pyrophosphate
• pyrophosphokinase
• thiamine
• thiazolone
• transketolase

Identity

International Standard Serial Number (ISSN)

• 0960-894X

Digital Object Identifier (DOI)

• 10.1016/j.bmcl.2007.11.098

PubMed ID

• 18182286

Additional Document Info

start page

• 509

end page

• 512

volume

• 18

issue

• 2