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Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that the transmission of malaria to mosquitoes

Academic Article
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Overview

authors

  • Vidadala, R. S. R.
  • Ojo, K. K.
  • Johnson, Steven
  • Zhang, Z.
  • Leonard, S. E.
  • Mitra, A.
  • Choi, R.
  • Reid, M. C.
  • Keyloun, K. R.
  • Fox, A. M. W.
  • Kennedy, M.
  • Silver-Brace, T.
  • Hume, J. C. C.
  • Kappe, S.
  • Verlinde, C. L.
  • Fan, E.
  • Merritt, E. A.
  • Van Voorhis, W. C.
  • Maly, D. J.

publication date

  • March 2014

journal

  • European Journal of Medicinal Chemistry  Journal

subject areas

  • Amino Acid Sequence
  • Animals
  • Antimalarials
  • Calcium
  • Malaria, Falciparum
  • Molecular Sequence Data
  • Plasmodium falciparum
  • Protein Kinase Inhibitors
  • Protein Kinases
  • Sequence Homology, Amino Acid
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Research

keywords

  • Exflagellation
  • PfCDPK1
  • PfCDPK4
  • Plasmodium falciparum
  • Pyrazolopyrimidine
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Identity

PubMed Central ID

  • PMC4024383

International Standard Serial Number (ISSN)

  • 0223-5234

Digital Object Identifier (DOI)

  • 10.1016/j.ejmech.2013.12.048

PubMed ID

  • 24531197
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Additional Document Info

start page

  • 562

end page

  • 573

volume

  • 74

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