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Design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from Escherichia coli

Academic Article
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Overview

authors

  • Chen, S.
  • Lin, Chun-Hung
  • Kwon, D. S.
  • Walsh, C. T.
  • Coward, J. K.

publication date

  • November 1997

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Amide Synthases
  • Bacterial Proteins
  • Drug Design
  • Enzyme Inhibitors
  • Escherichia coli
  • Glutathione
  • Kinetics
  • Organophosphonates
  • Phosphopeptides
  • Spermidine
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm970414b

PubMed ID

  • 9371250
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Additional Document Info

start page

  • 3842

end page

  • 3850

volume

  • 40

issue

  • 23

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